Giant Cell Tumors of the Axial Skeleton

المؤلفون المشاركون

Ahrens, Helmut
Koehler, Michael
Balke, Maurice
Henrichs, Marcel P.
Bullmann, Viola
Hardes, Jendrik
Streitbuerger, Arne
Gosheger, Georg

المصدر

Sarcoma

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-02-08

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Background.

We report on 19 cases of giant cell tumor of bone (GCT) affecting the spine or sacrum and evaluate the outcome of different treatment modalities.

Methods.

Nineteen patients with GCT of the spine (n=6) or sacrum (n=13) have been included in this study.

The mean followup was 51.6 months.

Ten sacral GCT were treated by intralesional procedures of which 4 also received embolization, and 3 with irradiation only.

All spinal GCT were surgically treated.

Results.

Two (15.4%) patients with sacral and 4 (66.7%) with spinal tumors had a local recurrence, two of the letter developed pulmonary metastases.

One local recurrence of the spine was successfully treated by serial arterial embolization, a procedure previously described only for sacral tumors.

At last followup, 9 patients had no evidence of disease, 8 had stable disease, 1 had progressive disease, 1 died due to disease.

Six patients had neurological deficits.

Conclusions.

GCT of the axial skeleton have a high local recurrence rate.

Neurological deficits are common.

En-bloc spondylectomy combined with embolization is the treatment of choice.

In case of inoperability, serial arterial embolization seems to be an alternative not only for sacral but also for spinal tumors.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Balke, Maurice& Henrichs, Marcel P.& Gosheger, Georg& Ahrens, Helmut& Streitbuerger, Arne& Koehler, Michael…[et al.]. 2012. Giant Cell Tumors of the Axial Skeleton. Sarcoma،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-470014

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Balke, Maurice…[et al.]. Giant Cell Tumors of the Axial Skeleton. Sarcoma No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-470014

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Balke, Maurice& Henrichs, Marcel P.& Gosheger, Georg& Ahrens, Helmut& Streitbuerger, Arne& Koehler, Michael…[et al.]. Giant Cell Tumors of the Axial Skeleton. Sarcoma. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-470014

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-470014