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Giant Cell Tumors of the Axial Skeleton
Joint Authors
Ahrens, Helmut
Koehler, Michael
Balke, Maurice
Henrichs, Marcel P.
Bullmann, Viola
Hardes, Jendrik
Streitbuerger, Arne
Gosheger, Georg
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
We report on 19 cases of giant cell tumor of bone (GCT) affecting the spine or sacrum and evaluate the outcome of different treatment modalities.
Methods.
Nineteen patients with GCT of the spine (n=6) or sacrum (n=13) have been included in this study.
The mean followup was 51.6 months.
Ten sacral GCT were treated by intralesional procedures of which 4 also received embolization, and 3 with irradiation only.
All spinal GCT were surgically treated.
Results.
Two (15.4%) patients with sacral and 4 (66.7%) with spinal tumors had a local recurrence, two of the letter developed pulmonary metastases.
One local recurrence of the spine was successfully treated by serial arterial embolization, a procedure previously described only for sacral tumors.
At last followup, 9 patients had no evidence of disease, 8 had stable disease, 1 had progressive disease, 1 died due to disease.
Six patients had neurological deficits.
Conclusions.
GCT of the axial skeleton have a high local recurrence rate.
Neurological deficits are common.
En-bloc spondylectomy combined with embolization is the treatment of choice.
In case of inoperability, serial arterial embolization seems to be an alternative not only for sacral but also for spinal tumors.
American Psychological Association (APA)
Balke, Maurice& Henrichs, Marcel P.& Gosheger, Georg& Ahrens, Helmut& Streitbuerger, Arne& Koehler, Michael…[et al.]. 2012. Giant Cell Tumors of the Axial Skeleton. Sarcoma،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-470014
Modern Language Association (MLA)
Balke, Maurice…[et al.]. Giant Cell Tumors of the Axial Skeleton. Sarcoma No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-470014
American Medical Association (AMA)
Balke, Maurice& Henrichs, Marcel P.& Gosheger, Georg& Ahrens, Helmut& Streitbuerger, Arne& Koehler, Michael…[et al.]. Giant Cell Tumors of the Axial Skeleton. Sarcoma. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-470014
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470014