![](/images/graphics-bg.png)
Contribution of 18F-Fluoro-ethyl-tyrosine Positron Emission Tomography to Target Volume Delineation in Stereotactic Radiotherapy of Malignant Cranial Base Tumours : First Clinical Experience
المؤلفون المشاركون
Graf, Reinhold
Fahdt, Daniel
Nyuyki, Fonyuy
Plotkin, Michail
Budach, Volker
Wust, Peter
Wurm, Reinhard
Brenner, Winfried
المصدر
International Journal of Molecular Imaging
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Increased amino acid uptake has been demonstrated in intracerebral tumours and head and neck carcinomas of squamous cell origin.
We investigated the potential impact of using 18F-fluoro-ethyl-tyrosine (18F-FET)-PET/CT in addition to conventional imaging for gross tumour volume (GTV) delineation in stereotactic radiotherapy of skull base tumours.
The study population consisted of 14 consecutive patients with cranial base tumours (10 with squamous cell histology, 4 others).
All patients underwent a FET-PET/CT examination in addition to contrast-enhanced CT and 11 patients underwent MRI.
All tumours and histologic types showed increased FET uptake.
The GTV was defined by all voxels showing hyperintensity in MRI or CT (GTVMRI/CT) or enhancement in PET (GTVPET), forming a GTVcomposite that was used for the initial treatment fields.
An additional volume of infiltrative growth outside the GTVMRI/CT of about 1.0 ± 2 cm3 (5% of the conventional volume) was demonstrated by FET-PET only (GTVPETplus) with significant enlargement (>10% of GTVMRI/CT) in three patients.
From existing data, we found correlation between cellular density and the standardized uptake value (SUV) of FET.
We were able to substantially reduce the volume of escalated radiation dose (GTVboost) by 11 ± 2 cm3 (24%) of the conventional volume.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Graf, Reinhold& Plotkin, Michail& Nyuyki, Fonyuy& Wust, Peter& Wurm, Reinhard& Budach, Volker…[et al.]. 2012. Contribution of 18F-Fluoro-ethyl-tyrosine Positron Emission Tomography to Target Volume Delineation in Stereotactic Radiotherapy of Malignant Cranial Base Tumours : First Clinical Experience. International Journal of Molecular Imaging،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-470076
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Graf, Reinhold…[et al.]. Contribution of 18F-Fluoro-ethyl-tyrosine Positron Emission Tomography to Target Volume Delineation in Stereotactic Radiotherapy of Malignant Cranial Base Tumours : First Clinical Experience. International Journal of Molecular Imaging No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-470076
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Graf, Reinhold& Plotkin, Michail& Nyuyki, Fonyuy& Wust, Peter& Wurm, Reinhard& Budach, Volker…[et al.]. Contribution of 18F-Fluoro-ethyl-tyrosine Positron Emission Tomography to Target Volume Delineation in Stereotactic Radiotherapy of Malignant Cranial Base Tumours : First Clinical Experience. International Journal of Molecular Imaging. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-470076
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470076
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)