Role of PPARα in the Control of Torpor through FGF21-NPY Pathway : From Circadian Clock to Seasonal Change in Mammals

المؤلف

Ishida, Norio

المصدر

PPAR Research

العدد

المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2009-06-07

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء

الملخص EN

In nature, hibernating animals encounter fasting, cold temperature and short day seasonally.

Torpor is a state of decreased physiological activity in an animal, usually characterized by a reduced body temperature and rate of metabolism to adapt such a severe environment.

Ablation of the central clock synchronizer, the suprachiasmatic nucleus in brain, abolishes torpor, a hibernation-like state, implicating the circadian clock involved in this seasonal change.

Biologists knows well the energy source of daily heterotherms/hibernators changed from glucose to lipids in winter.

Here we review several lines of evidence of a master transcriptional regulator in lipid catabolism, PPARα, in the control of torpor through FGF21-NPY pathway.

This indicate the importance of circadian—and photoperiod—regulation of PPARα to tell seasons in our body.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ishida, Norio. 2009. Role of PPARα in the Control of Torpor through FGF21-NPY Pathway : From Circadian Clock to Seasonal Change in Mammals. PPAR Research،Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-470125

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ishida, Norio. Role of PPARα in the Control of Torpor through FGF21-NPY Pathway : From Circadian Clock to Seasonal Change in Mammals. PPAR Research No. 2009 (2009), pp.1-5.
https://search.emarefa.net/detail/BIM-470125

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ishida, Norio. Role of PPARα in the Control of Torpor through FGF21-NPY Pathway : From Circadian Clock to Seasonal Change in Mammals. PPAR Research. 2009. Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-470125

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-470125