The Impact of Hyperglycemia on Risk of Severe Infections during Early Period of Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma
المؤلفون المشاركون
Kim, Yeo-Kyeoung
Jung, Sung-Hoon
Jang, Hee-Chang
Lee, Seung-Shin
Ahn, Jae-Sook
Yang, Deok-Hwan
Lee, Je-Jung
Kim, Hyeoung-Joon
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-16
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The association between hyperglycemia and infections during induction chemotherapy has been reported in a number of hematologic disorders.
This retrospective study evaluated the incidence of hyperglycemia during induction therapy in 155 patients with newly diagnosed multiple myeloma (MM) and its effect on serious infections during the first 60 days of induction.
A total of 20 (12.9%) patients developed overt hyperglycemia (≥200 mg/dL) during induction therapy.
Serious infections occurred in 28 (18.1%) of 155 patients and infection-related mortality within 2 months after treatment was 0.6% (1 patient).
In a univariate analysis, overt hyperglycemia, poor performance status (≥2), International Staging System III, lymphopenia (<500/μL), and elevated serum creatinine (≥2 mg/dL) were found to be associated with serious infections.
In multivariate analysis, only overt hyperglycemia (HR 7.846, 95% CI 2.512–24.503, P<0.001) and poor performance status (HR 5.801, 95% CI 1.974–17.050, P=0.001) remained significant.
In conclusion, this study demonstrated an association between hyperglycemia and serious infections during induction therapy in patients with MM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jung, Sung-Hoon& Jang, Hee-Chang& Lee, Seung-Shin& Ahn, Jae-Sook& Yang, Deok-Hwan& Kim, Yeo-Kyeoung…[et al.]. 2014. The Impact of Hyperglycemia on Risk of Severe Infections during Early Period of Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-470144
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jung, Sung-Hoon…[et al.]. The Impact of Hyperglycemia on Risk of Severe Infections during Early Period of Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-470144
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jung, Sung-Hoon& Jang, Hee-Chang& Lee, Seung-Shin& Ahn, Jae-Sook& Yang, Deok-Hwan& Kim, Yeo-Kyeoung…[et al.]. The Impact of Hyperglycemia on Risk of Severe Infections during Early Period of Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-470144
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470144
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر