Subacute and Reproductive Oral Toxicity Assessment of the Hydroethanolic Extract of Jacaranda decurrens Roots in Adult Male Rats
المؤلفون المشاركون
Cardoso, Claudia Andrea Lima
Santos, Joyce Alencar
Arruda, Aline
Kassuya, Cândida Aparecida Leite
Piccinelli, Ana Cláudia
Arena, Arielle Cristina
Vieira, Maria do Carmo
Figueiredo de Santana Aquino, Diana
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Jacaranda decurrens subsp.
symmetrifoliolata Farias & Proença (Bignoniaceae) is a species traditionally used for the treatment of inflammatory and infectious diseases.
Previous findings from our group reported scientifically that J.
decurrens has anti-inflammatory efficacy.
However, more toxicological studies are needed to support and ensure its safe use.
The present study was carried out to evaluate the toxic effects of a prolonged treatment with hydroethanolic root extract of J.
decurrens (EJD) on hematological, biochemical, and reproductive parameters in adult male rats.
The animals received by oral gavage 0; 250; 500; or 1000 mg/kg body weight of EJD for 28 days.
After the treatment, biochemical, hematological, histopathological, and reproductive parameters were analyzed.
The EJD treatment did not cause adverse effects on body weight gain, feed and water consumption, hematological and biochemical profiles, or histopathological analysis of liver and kidney.
Similarly, there were no statistically significant differences in reproductive parameters, such as sperm production, number of sperm in the epididymis, and sperm morphology.
These results demonstrate the absence of subacute toxicity as a result of the oral treatment with EJD for 28 days in adult male rats.
However, other studies should be performed to evaluate the total safety of this plant.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Santos, Joyce Alencar& Arruda, Aline& Cardoso, Claudia Andrea Lima& Vieira, Maria do Carmo& Piccinelli, Ana Cláudia& Figueiredo de Santana Aquino, Diana…[et al.]. 2013. Subacute and Reproductive Oral Toxicity Assessment of the Hydroethanolic Extract of Jacaranda decurrens Roots in Adult Male Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-470292
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Santos, Joyce Alencar…[et al.]. Subacute and Reproductive Oral Toxicity Assessment of the Hydroethanolic Extract of Jacaranda decurrens Roots in Adult Male Rats. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-470292
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Santos, Joyce Alencar& Arruda, Aline& Cardoso, Claudia Andrea Lima& Vieira, Maria do Carmo& Piccinelli, Ana Cláudia& Figueiredo de Santana Aquino, Diana…[et al.]. Subacute and Reproductive Oral Toxicity Assessment of the Hydroethanolic Extract of Jacaranda decurrens Roots in Adult Male Rats. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-470292
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470292
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر