![](/images/graphics-bg.png)
Have Changes in Systemic Treatment Improved Survival in Patients with Breast Cancer Metastatic to the Brain?
المؤلفون المشاركون
Nieder, Carsten
Dalhaug, Astrid
Norum, Jan
Marienhagen, Kirsten
المصدر
العدد
المجلد 2008، العدد 2008 (31 ديسمبر/كانون الأول 2008)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2008-09-23
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Newly developed systemic treatment regimens might lead to improved survival also in the subgroup of breast cancer patients that harbour brain metastases.
In order to examine this hypothesis, a matched pairs analysis was performed that involved one group of patients, which were treated after these new drugs were introduced, and one group of patients, which were treated approximately 10 years earlier.
The two groups were well balanced for the known prognostic factors age, KPS, extracranial disease status, and recursive partitioning analysis class, as well as for the extent of brain treatment.
The results show that the use of systemic chemotherapy has increased over time, both before and after the diagnosis of brain metastases.
However, such treatment was performed nearly exclusively in those patients with brain metastases that belonged to the prognostically more favourable groups.
Survival after whole-brain radiotherapy has remained unchanged in patients without further active treatment.
It has improved in prognostically better patients and especially patients that received active treatment, where the 1-year survival rates have almost doubled.
As these patient groups were small, confirmation of the results in other series should be attempted.
Nevertheless, the present results are compatible with the hypothesis that improved systemic therapy might contribute to prolonged survival in patients with brain metastases from breast cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nieder, Carsten& Marienhagen, Kirsten& Dalhaug, Astrid& Norum, Jan. 2008. Have Changes in Systemic Treatment Improved Survival in Patients with Breast Cancer Metastatic to the Brain?. Journal of Oncology،Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-470517
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nieder, Carsten…[et al.]. Have Changes in Systemic Treatment Improved Survival in Patients with Breast Cancer Metastatic to the Brain?. Journal of Oncology No. 2008 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-470517
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nieder, Carsten& Marienhagen, Kirsten& Dalhaug, Astrid& Norum, Jan. Have Changes in Systemic Treatment Improved Survival in Patients with Breast Cancer Metastatic to the Brain?. Journal of Oncology. 2008. Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-470517
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470517
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)