Prevalence of Thyroid Autoimmunity in Children with Celiac Disease Compared to Healthy 12-Year Olds
المؤلفون المشاركون
Svensson, Johan
Ivarsson, Anneli
Högberg, Lotta
Carlsson, Annelie
Norström, Fredrik
van der Pals, Maria
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-27
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
Studies have suggested a correlation between untreated celiac disease and risk for other autoimmune diseases.
We investigated the prevalence of thyroid autoimmunity in 12-year-old children (i) with symptomatic celiac disease diagnosed and treated with a gluten-free diet, (ii) with screening-detected untreated celiac disease, and (iii) without celiac disease.
Methods.
Blood samples from 12632 children were collected.
All celiac disease cases, previously diagnosed and newly screening-detected, were identified.
Per case, 4 referents were matched.
Blood samples were analyzed for autoantibodies against thyroid peroxidase (TPOAb).
The cut-off value for TPO positivity was set to 100 U/mL.
Results.
Altogether, 335 celiac disease cases were found.
In the entire celiac disease group, 7.2% (24/335) had elevated titers of TPOAb compared to 2.8% (48/1695) of the referents.
Among the previously diagnosed celiac disease cases, 7.5% (7/93, OR 2.8, 95% CI 1.2–6.4) was TPOAb positive and among screening-detected cases, 7.0% (17/242, OR 2.6, 95% CI 1.5–4.6) was TPOAb positive.
Conclusion.
Children with celiac disease showed a higher prevalence of thyroid autoimmunity.
We could not confirm the hypothesis that untreated celiac disease is associated with increased risk of developing thyroid autoimmunity.
Early initiation of celiac disease treatment might not lower the risk for other autoimmune diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
van der Pals, Maria& Ivarsson, Anneli& Norström, Fredrik& Högberg, Lotta& Svensson, Johan& Carlsson, Annelie. 2014. Prevalence of Thyroid Autoimmunity in Children with Celiac Disease Compared to Healthy 12-Year Olds. Autoimmune Diseases،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-470536
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
van der Pals, Maria…[et al.]. Prevalence of Thyroid Autoimmunity in Children with Celiac Disease Compared to Healthy 12-Year Olds. Autoimmune Diseases No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-470536
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
van der Pals, Maria& Ivarsson, Anneli& Norström, Fredrik& Högberg, Lotta& Svensson, Johan& Carlsson, Annelie. Prevalence of Thyroid Autoimmunity in Children with Celiac Disease Compared to Healthy 12-Year Olds. Autoimmune Diseases. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-470536
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470536
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر