The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients
المؤلفون المشاركون
Arikan, Ender
Berkarda, Sakir
Tuglu, Cengiz
Soylu, Ali Riza
Koker, Ibrahim Hakki
Yetisyigit, Tarkan
Kunduracılar, Hakan
Umit, Hasan
Unsal, Gulbin
Tezel, Ahmet Huseyin
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
In this study, we aimed to investigate the possible role of serum cytokines in the development of hepatic osteodystrophy.
Matherial and Methods.
44 consecutive male cirrhotic patients (17 alcoholic, 20 hepatitis B, 7 hepatitis C), 15 age- and sex-matched chronic alcoholics without liver disease, and 17 age- and sex-matched healthy controls were included in the study during one year period.
Bone mineral density was measured by dual X-ray absorptiometry in the lumbar vertebrate and femoral neck.
Serum interleukin levels were measured by ELISA method.
Results.
Although osteopenia frequency between our cirrhotic patients was 20%, there was no difference in T-scores among the controls and other groups.
Serum interleukin-1, interleukin-8, and tumor necrosis factor-alpha levels were not different between all groups.
Serum interleukin-2 and interleukin-6 levels were higher in the cirrhotics than controls (P<0.001).
However, there were no significant difference between osteopenic and nonosteopenic cirrhotics.
Conclusion.
According to the results of the study in this small population of 44 male cirrhotic patients, frequency of hepatic osteopenia is small and serum interleukins 1, 2, 6, 8, and tumor necrosis factor-alpha may not play a role in the pathogenesis of hepatic osteodystrophy.
Further studies in which large number of patients involved are necessary in this field.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Soylu, Ali Riza& Tuglu, Cengiz& Arikan, Ender& Yetisyigit, Tarkan& Kunduracılar, Hakan& Koker, Ibrahim Hakki…[et al.]. 2012. The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-471154
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Soylu, Ali Riza…[et al.]. The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients. Gastroenterology Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-471154
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Soylu, Ali Riza& Tuglu, Cengiz& Arikan, Ender& Yetisyigit, Tarkan& Kunduracılar, Hakan& Koker, Ibrahim Hakki…[et al.]. The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-471154
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471154
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر