![](/images/graphics-bg.png)
Characterization of Myelomonocytoid Progenitor Cells with Mesenchymal Differentiation Potential Obtained by Outgrowth from Pancreas Explants
المؤلفون المشاركون
Roehrich, Marc-Estienne
Vassalli, Giuseppe
المصدر
Biotechnology Research International
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-21
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Progenitor cells can be obtained by outgrowth from tissue explants during primary ex vivo tissue culture.
We have isolated and characterized cells outgrown from neonatal mouse pancreatic explants.
A relatively uniform population of cells showing a distinctive morphology emerged over time in culture.
This population expressed monocyte/macrophage and hematopoietic markers (CD11b+ and CD45+), and some stromal-related markers (CD44+ and CD29+), but not mesenchymal stem cell (MSC)-defining markers (CD90− and CD105−) nor endothelial (CD31−) or stem cell-associated markers (CD133− and stem cell antigen-1; Sca-1−).
Cells could be maintained in culture as a plastic-adherent monolayer in culture medium (MesenCult MSC) for more than 1 year.
Cells spontaneously formed sphere clusters “pancreatospheres” which, however, were nonclonal.
When cultured in appropriate media, cells differentiated into multiple mesenchymal lineages (fat, cartilage, and bone).
Positive dithizone staining suggested that a subset of cells differentiated into insulin-producing cells.
However, further studies are needed to characterize the endocrine potential of these cells.
These findings indicate that a myelomonocytoid population from pancreatic explant outgrowths has mesenchymal differentiation potential.
These results are in line with recent data onmonocyte-derivedmesenchymal progenitors (MOMPs).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Roehrich, Marc-Estienne& Vassalli, Giuseppe. 2012. Characterization of Myelomonocytoid Progenitor Cells with Mesenchymal Differentiation Potential Obtained by Outgrowth from Pancreas Explants. Biotechnology Research International،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-471628
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Roehrich, Marc-Estienne& Vassalli, Giuseppe. Characterization of Myelomonocytoid Progenitor Cells with Mesenchymal Differentiation Potential Obtained by Outgrowth from Pancreas Explants. Biotechnology Research International No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-471628
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Roehrich, Marc-Estienne& Vassalli, Giuseppe. Characterization of Myelomonocytoid Progenitor Cells with Mesenchymal Differentiation Potential Obtained by Outgrowth from Pancreas Explants. Biotechnology Research International. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-471628
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471628
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)