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Fortified Extract of Red Berry, Ginkgo biloba, and White Willow Bark in Experimental Early Diabetic Retinopathy
المؤلفون المشاركون
Marrazzo, Giuseppina
Drago, Filippo
Leggio, Gian Marco
Bucolo, Claudio
Salomone, Salvatore
Platania, Chiara Bianca Maria
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-23
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Diabetic retinopathy is a complex condition where inflammation and oxidative stress represent crucial pathways in the pathogenesis of the disease.
Aim of the study was to investigate the effects of a fortified extract of red berries, Ginkgo biloba and white willow bark containing carnosine and α-lipoic acid in early retinal and plasma changes of streptozotocin-induced diabetic rats.
Diabetes was induced by a single streptozotocin injection in Sprague Dawley rats.
Diabetics and nondiabetic (control) rats were treated daily with the fortified extract for the ten days.
Retina samples were collected and analyzed for their TNF-α and VEGF content.
Moreover, plasma oxidative stress was evaluated by thiobarbituric acid reacting substances (TBARS).
Increased TNF-α and VEGF levels were observed in the retina of diabetic rats.
Treatment with the fortified extract significantly lowered retinal cytokine levels and suppressed diabetes-related lipid peroxidation.
These data demonstrate that the fortified extract attenuates the degree of retinal inflammation and plasma lipid peroxidation preserving the retina in early diabetic rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bucolo, Claudio& Marrazzo, Giuseppina& Platania, Chiara Bianca Maria& Drago, Filippo& Leggio, Gian Marco& Salomone, Salvatore. 2013. Fortified Extract of Red Berry, Ginkgo biloba, and White Willow Bark in Experimental Early Diabetic Retinopathy. Journal of Diabetes Research،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-471875
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bucolo, Claudio…[et al.]. Fortified Extract of Red Berry, Ginkgo biloba, and White Willow Bark in Experimental Early Diabetic Retinopathy. Journal of Diabetes Research No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-471875
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bucolo, Claudio& Marrazzo, Giuseppina& Platania, Chiara Bianca Maria& Drago, Filippo& Leggio, Gian Marco& Salomone, Salvatore. Fortified Extract of Red Berry, Ginkgo biloba, and White Willow Bark in Experimental Early Diabetic Retinopathy. Journal of Diabetes Research. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-471875
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471875
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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