Nanofibrous Chitosan-Polyethylene Oxide Engineered Scaffolds : A Comparative Study between Simulated Structural Characteristics and Cells Viability
المؤلفون المشاركون
Kazemi Pilehrood, Mohammad
Harlin, Ali
Mirian, Mina
Dilamian, Mandana
Maleknia, Laleh
Nousiainen, Pertti
Sadeghi-Aliabadi, Hojjat
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-04
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
3D nanofibrous chitosan-polyethylene oxide (PEO) scaffolds were fabricated by electrospinning at different processing parameters.
The structural characteristics, such as pore size, overall porosity, pore interconnectivity, and scaffold percolative efficiency (SPE), were simulated by a robust image analysis.
Mouse fibroblast cells (L929) were cultured in RPMI for 2 days in the presence of various samples of nanofibrous chitosan/PEO scaffolds.
Cell attachments and corresponding mean viability were enhanced from 50% to 110% compared to that belonging to a control even at packed morphologies of scaffolds constituted from pores with nanoscale diameter.
To elucidate the correlation between structural characteristics within the depth of the scaffolds’ profile and cell viability, a comparative analysis was proposed.
This analysis revealed that larger fiber diameters and pore sizes can enhance cell viability.
On the contrary, increasing the other structural elements such as overall porosity and interconnectivity due to a simultaneous reduction in fiber diameter and pore size through the electrospinning process can reduce the viability of cells.
In addition, it was found that manipulation of the processing parameters in electrospinning can compensate for the effects of packed morphologies of nanofibrous scaffolds and can thus potentially improve the infiltration and viability of cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kazemi Pilehrood, Mohammad& Dilamian, Mandana& Mirian, Mina& Sadeghi-Aliabadi, Hojjat& Maleknia, Laleh& Nousiainen, Pertti…[et al.]. 2014. Nanofibrous Chitosan-Polyethylene Oxide Engineered Scaffolds : A Comparative Study between Simulated Structural Characteristics and Cells Viability. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-472320
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kazemi Pilehrood, Mohammad…[et al.]. Nanofibrous Chitosan-Polyethylene Oxide Engineered Scaffolds : A Comparative Study between Simulated Structural Characteristics and Cells Viability. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-472320
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kazemi Pilehrood, Mohammad& Dilamian, Mandana& Mirian, Mina& Sadeghi-Aliabadi, Hojjat& Maleknia, Laleh& Nousiainen, Pertti…[et al.]. Nanofibrous Chitosan-Polyethylene Oxide Engineered Scaffolds : A Comparative Study between Simulated Structural Characteristics and Cells Viability. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-472320
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-472320
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر