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Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit
المؤلفون المشاركون
Moreira, Magna S. A.
Falcao, Rosangela A.
do Nascimento, Patricia L. A.
Alves de Souza, Silvana
da Matta, Carolina B. B.
da Silva, Telma M. G.
Silva, Tania Maria Sarmento
de Queiroz, Aline C.
Camara, Celso Amorim
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-28
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Hyptis pectinata, popularly known in Brazil as “sambacaitá” or “canudinho,” is an aromatic shrub largely grown in the northeast of Brazil.
The leaves and bark are used in an infusion for the treatment of throat and skin inflammations, bacterial infections, pain, and cancer.
Analogues of rosmarinic acid and flavonoids were obtained from the leaves of Hyptis pectinata and consisted of two new compounds, sambacaitaric acid (1) and 3-O-methyl-sambacaitaric acid (2), and nine known compounds, rosmarinic acid (3), 3-O-methyl-rosmarinic acid (4), ethyl caffeate (5), nepetoidin A (6), nepetoidin B (7), cirsiliol (8), circimaritin (9), 7-O-methylluteolin (10), and genkwanin (11).
The structures of these compounds were determined by spectroscopic methods.
Compounds 1–5, and 7 were evaluated in vitro against the promastigote form of L.
braziliensis, and the ethanol extract.
The hexane, ethyl acetate, and methanol-water fractions were also evaluated.
The EtOH extract, the hexane extract, EtOAc, MeOH:H2O fractions; and compounds 1, 2 and 4 exhibited antileishmanial activity, and compound 1 was as potent as pentamidine.
In contrast, compounds 3, 5, and 7 did not present activity against the promastigote form of L.
braziliensis below 100 µM.
To our knowledge, compounds 1 and 2 are being described for the first time.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Falcao, Rosangela A.& do Nascimento, Patricia L. A.& Alves de Souza, Silvana& da Silva, Telma M. G.& de Queiroz, Aline C.& da Matta, Carolina B. B.…[et al.]. 2013. Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-473315
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Falcao, Rosangela A.…[et al.]. Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-473315
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Falcao, Rosangela A.& do Nascimento, Patricia L. A.& Alves de Souza, Silvana& da Silva, Telma M. G.& de Queiroz, Aline C.& da Matta, Carolina B. B.…[et al.]. Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-473315
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473315
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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