Complement Attack against Aspergillus and Corresponding Evasion Mechanisms
المؤلفون المشاركون
Rambach, Günter
Speth, Cornelia
المصدر
Interdisciplinary Perspectives on Infectious Diseases
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Invasive aspergillosis shows a high mortality rate particularly in immunocompromised patients.
Perpetually increasing numbers of affected patients highlight the importance of a clearer understanding of interactions between innate immunity and fungi.
Innate immunity is considered to be the most significant host defence against invasive fungal infections.
Complement represents a crucial part of this first line defence and comprises direct effects against invading pathogens as well as bridging functions to other parts of the immune network.
However, despite the potency of complement to attack foreign pathogens, the prevalence of invasive fungal infections is increasing.
Two possible reasons may explain that phenomenon: First, complement activation might be insufficient for an effective antifungal defence in risk patients (due to, e.g., low complement levels, poor recognition of fungal surface, or missing interplay with other immune elements in immunocompromised patients).
On the other hand, fungi may have developed evasion strategies to avoid recognition and/or eradication by complement.
In this review, we summarize the most important interactions between Aspergillus and the complement system.
We describe the various ways of complement activation by Aspergillus and the antifungal effects of the system, and also show proven and probable mechanisms of Aspergillus for complement evasion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Speth, Cornelia& Rambach, Günter. 2012. Complement Attack against Aspergillus and Corresponding Evasion Mechanisms. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-473608
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Speth, Cornelia& Rambach, Günter. Complement Attack against Aspergillus and Corresponding Evasion Mechanisms. Interdisciplinary Perspectives on Infectious Diseases No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-473608
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Speth, Cornelia& Rambach, Günter. Complement Attack against Aspergillus and Corresponding Evasion Mechanisms. Interdisciplinary Perspectives on Infectious Diseases. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-473608
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473608
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر