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Long-Term Outcomes for Patients with Prostate Cancer Having Intermediate and High-Risk Disease, Treated with Combination External Beam Irradiation and Brachytherapy
المؤلفون المشاركون
Bostwick, David
Cash, Jennifer
Wallner, Kent
Dattoli, Michael
True, Lawrence
Sorace, Richard
المصدر
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-08-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Perception remains that brachytherapy-based regimens are inappropriate for patients having increased risk of extracapsular extension (ECE).
Methods.
321 consecutive intermediate and high-risk disease patients were treated between 1/92 and 2/97 by one author (M.
Dattoli) and stratified by NCCN guidelines.
157 had intermediate-risk; 164 had high-risk disease.
All were treated using the combination EBRT/brachytherapy ± hormones.
Biochemical failure was defined using PSA >0.2 and nadir +2 at last followup.
Nonfailing patients followup was median 10.5 years.
Both biochemical data and original biopsy slides were independently rereviewed at an outside institution.
Results.
Overall actuarial freedom from biochemical progression at 16 years was 82% (89% intermediate, 74% high-risk) with failure predictors: Gleason score (P=.01) and PSA (P=.03).
Hormonal therapy did not affect failure rates (P=.14).
Conclusion.
This study helps to strengthen the rationale for brachytherapy-based regimens as being both durable and desirable treatment options for such patients.
Prospective studies are justified to confirm these positive results.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dattoli, Michael& Wallner, Kent& True, Lawrence& Bostwick, David& Cash, Jennifer& Sorace, Richard. 2010. Long-Term Outcomes for Patients with Prostate Cancer Having Intermediate and High-Risk Disease, Treated with Combination External Beam Irradiation and Brachytherapy. Journal of Oncology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-474128
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dattoli, Michael…[et al.]. Long-Term Outcomes for Patients with Prostate Cancer Having Intermediate and High-Risk Disease, Treated with Combination External Beam Irradiation and Brachytherapy. Journal of Oncology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-474128
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dattoli, Michael& Wallner, Kent& True, Lawrence& Bostwick, David& Cash, Jennifer& Sorace, Richard. Long-Term Outcomes for Patients with Prostate Cancer Having Intermediate and High-Risk Disease, Treated with Combination External Beam Irradiation and Brachytherapy. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-474128
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-474128
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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