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The Application of Functional Magnetic Resonance Imaging in an Infant Rat Model of Irritable Bowel Syndrome
المؤلفون المشاركون
Zhu, Xueping
Chen, Jianhua
Chen, Weichang
Zhu, Xiaoli
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-30
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
The aim of this study was to use functional magnetic resonance imaging (BOLD-fMRI) to investigate the activated region associated with visceral pain in the brains of infant rats in a model of IBS.
Sixteen newborn rats were randomized into an IBS model group and a control group.
Those in the IBS group were separated from their mothers and were mechanically immobilized and had rectal sensitization with mustard essential oil for 1 week.
The control group had no treatment.
After 2 weeks, balloon catheters were inflated with 5 or 10 mL of air in the rectums of both groups.
BOLD-fMRI was performed and the data analyzed by imaging software.
In the IBS model group, rectal stimulation with 5 mL air distension activated the anterior cingulate cortex, insula cortex (IC), prefrontal cortex (PFC), and thalamus, while 10 mL air significantly activated the ACC, IC, PFC, and thalamus in the model, but not controls.
IBS model group was hypersensitive to visceral stimulation by rectal balloon inflation.
The major brain areas participating in visceral sensation included the IC, PFC, and thalamus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhu, Xueping& Zhu, Xiaoli& Chen, Weichang& Chen, Jianhua. 2014. The Application of Functional Magnetic Resonance Imaging in an Infant Rat Model of Irritable Bowel Syndrome. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-474375
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhu, Xueping…[et al.]. The Application of Functional Magnetic Resonance Imaging in an Infant Rat Model of Irritable Bowel Syndrome. Gastroenterology Research and Practice No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-474375
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhu, Xueping& Zhu, Xiaoli& Chen, Weichang& Chen, Jianhua. The Application of Functional Magnetic Resonance Imaging in an Infant Rat Model of Irritable Bowel Syndrome. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-474375
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-474375
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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