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A Simple Model to Assess the Probability of Invasion in Ductal Carcinoma In Situ of the Breast Diagnosed by Needle Biopsy
المؤلفون المشاركون
Stískalová, Kateřina
Fabian, Pavel
Selingerová, Iveta
Coufal, Oldřich
Schneiderová, Monika
Krsička, Petr
Gabrielová, Lucie
Justan, Ivan
Poprach, Alexandr
Vrtělová, Pavlína
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-08
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
The aim of the study was to develop a clinical prediction model for assessing the probability of having invasive cancer in the definitive surgical resection specimen in patients with biopsy diagnosis of ductal carcinoma in situ (DCIS) of the breast, to facilitate decision making regarding axillary surgery.
Methods.
In 349 women with DCIS, predictors of invasion in the definitive resection specimen were identified.
A model to predict the probability of invasion was developed and subsequently simplified to divide patients into two risk categories.
The model’s performance was validated on another patient population.
Results.
Multivariate logistic regression revealed four independent predictors of invasion: (i) suspicious (micro)invasion in the biopsy specimen; (ii) visibility of the lesion on ultrasonography; (iii) size of the lesion on mammography >30 mm; (iv) clinical palpability of the lesion.
The actual frequency of invasion in the high-risk patient group in the test and validation population was 52.6% and 48.3%, respectively; in the low-risk group it was 16.8% and 7.1%, respectively.
Conclusion.
The model proved to have good performance.
In patients with a low probability of invasion, an axillary procedure can be omitted without a substantial risk of additional surgery.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Coufal, Oldřich& Selingerová, Iveta& Vrtělová, Pavlína& Krsička, Petr& Gabrielová, Lucie& Fabian, Pavel…[et al.]. 2014. A Simple Model to Assess the Probability of Invasion in Ductal Carcinoma In Situ of the Breast Diagnosed by Needle Biopsy. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-474943
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Coufal, Oldřich…[et al.]. A Simple Model to Assess the Probability of Invasion in Ductal Carcinoma In Situ of the Breast Diagnosed by Needle Biopsy. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-474943
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Coufal, Oldřich& Selingerová, Iveta& Vrtělová, Pavlína& Krsička, Petr& Gabrielová, Lucie& Fabian, Pavel…[et al.]. A Simple Model to Assess the Probability of Invasion in Ductal Carcinoma In Situ of the Breast Diagnosed by Needle Biopsy. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-474943
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-474943
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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