Investigating the Feasibility of Rapid MRI for Image-Guided Motion Management in Lung Cancer Radiotherapy
المؤلفون المشاركون
Loo Jr., Billy W.
Keall, Paul
Hinkle, Jacob
Sawant, Amit
Alley, Marcus
Joshi, Sarang
Vasanawala, Shreyas
Pauly, Kim Butts
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-12
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Cycle-to-cycle variations in respiratory motion can cause significant geometric and dosimetric errors in the administration of lung cancer radiation therapy.
A common limitation of the current strategies for motion management is that they assume a constant, reproducible respiratory cycle.
In this work, we investigate the feasibility of using rapid MRI for providing long-term imaging of the thorax in order to better capture cycle-to-cycle variations.
Two nonsmall-cell lung cancer patients were imaged (free-breathing, no extrinsic contrast, and 1.5 T scanner).
A balanced steady-state-free-precession (b-SSFP) sequence was used to acquire cine-2D and cine-3D (4D) images.
In the case of Patient 1 (right midlobe lesion, ~40 mm diameter), tumor motion was well correlated with diaphragmatic motion.
In the case of Patient 2, (left upper-lobe lesion, ~60 mm diameter), tumor motion was poorly correlated with diaphragmatic motion.
Furthermore, the motion of the tumor centroid was poorly correlated with the motion of individual points on the tumor boundary, indicating significant rotation and/or deformation.
These studies indicate that image quality and acquisition speed of cine-2D MRI were adequate for motion monitoring.
However, significant improvements are required to achieve comparable speeds for truly 4D MRI.
Despite several challenges, rapid MRI offers a feasible and attractive tool for noninvasive, long-term motion monitoring.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sawant, Amit& Keall, Paul& Pauly, Kim Butts& Alley, Marcus& Vasanawala, Shreyas& Loo Jr., Billy W.…[et al.]. 2014. Investigating the Feasibility of Rapid MRI for Image-Guided Motion Management in Lung Cancer Radiotherapy. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-475348
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sawant, Amit…[et al.]. Investigating the Feasibility of Rapid MRI for Image-Guided Motion Management in Lung Cancer Radiotherapy. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-475348
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sawant, Amit& Keall, Paul& Pauly, Kim Butts& Alley, Marcus& Vasanawala, Shreyas& Loo Jr., Billy W.…[et al.]. Investigating the Feasibility of Rapid MRI for Image-Guided Motion Management in Lung Cancer Radiotherapy. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-475348
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-475348
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر