Ovarian Carcinosarcoma : Effects of Cytoreductive Status and Platinum-Based Chemotherapy on Survival
المؤلفون المشاركون
Tseng, Jill H.
Nutter, Benjamin
Escobar, Pedro F.
Jernigan, Amelia M.
Rose, Peter
Fader, Amanda Nickles
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-27
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To define survival patterns of women with ovarian carcinosarcoma based on patient, tumor, and treatment characteristics.
Methods/Materials.
A single-institution, retrospective analysis of women diagnosed with ovarian carcinosarcoma from February 1993 to May 2009 was performed.
Survival was analyzed with Cox proportional hazards ratios and Kaplan Meier tests.
Results.
Forty-seven cases of primary ovarian carcinosarcoma were identified.
Age conveyed an HR 3.28 (95% CI 1.51–7.11, P=0.003) for death.
Compared to Stages I-II, Stage III carried an HR for death of 4.75 (95% CI 1.16–19.4, P=0.03) and Stage IV disease an HR of 9.13 (95% CI 1.76–47.45, P=0.009).
Compared to those with microscopic residual, women with >1 cm diameter of residual disease after primary cytoreductive surgery had an HR for death of 4.71 (95% CI 1.84–12.09, P=0.001).
At analysis, 59.1% of those who received platinum-based chemotherapy were alive, compared to 23.1% of those who received nonplatinum-based chemotherapy (P=0.08).
Conclusions.
Age, stage, and cytoreduction to no gross residual disease are associated with improved survival in women with ovarian carcinosarcoma.
Complete surgical cytoreduction should be the goal of surgical management when possible, but the ideal adjuvant treatment regimen remains unclear.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jernigan, Amelia M.& Fader, Amanda Nickles& Nutter, Benjamin& Rose, Peter& Tseng, Jill H.& Escobar, Pedro F.. 2013. Ovarian Carcinosarcoma : Effects of Cytoreductive Status and Platinum-Based Chemotherapy on Survival. Obstetrics and Gynecology International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-475773
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jernigan, Amelia M.…[et al.]. Ovarian Carcinosarcoma : Effects of Cytoreductive Status and Platinum-Based Chemotherapy on Survival. Obstetrics and Gynecology International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-475773
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jernigan, Amelia M.& Fader, Amanda Nickles& Nutter, Benjamin& Rose, Peter& Tseng, Jill H.& Escobar, Pedro F.. Ovarian Carcinosarcoma : Effects of Cytoreductive Status and Platinum-Based Chemotherapy on Survival. Obstetrics and Gynecology International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-475773
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-475773
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر