ER-Mitochondria Crosstalk during Cerebral Ischemia : Molecular Chaperones and ER-Mitochondrial Calcium Transfer

المؤلفون المشاركون

Ouyang, Yi-Bing
Giffard, Rona G.

المصدر

International Journal of Cell Biology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-04-02

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأحياء

الملخص EN

It is commonly believed that sustained elevations in the mitochondrial matrix Ca2+ concentration are a major feature of the intracellular cascade of lethal events during cerebral ischemia.

The physical association between the endoplasmic reticulum (ER) and mitochondria, known as the mitochondria-associated ER membrane (MAM), enables highly efficient transmission of Ca2+ from the ER to mitochondria under both physiological and pathological conditions.

Molecular chaperones are well known for their protective effects during cerebral ischemia.

It has been demonstrated recently that many molecular chaperones coexist with MAM and regulate the MAM and thus Ca2+ concentration inside mitochondria.

Here, we review recent research on cerebral ischemia and MAM, with a focus on molecular chaperones and ER-mitochondrial calcium transfer.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ouyang, Yi-Bing& Giffard, Rona G.. 2012. ER-Mitochondria Crosstalk during Cerebral Ischemia : Molecular Chaperones and ER-Mitochondrial Calcium Transfer. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-476112

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ouyang, Yi-Bing& Giffard, Rona G.. ER-Mitochondria Crosstalk during Cerebral Ischemia : Molecular Chaperones and ER-Mitochondrial Calcium Transfer. International Journal of Cell Biology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-476112

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ouyang, Yi-Bing& Giffard, Rona G.. ER-Mitochondria Crosstalk during Cerebral Ischemia : Molecular Chaperones and ER-Mitochondrial Calcium Transfer. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-476112

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-476112