Analysis of Extrahepatic Multiple Primary Malignancies in Patients with Hepatocellular Carcinoma according to Viral Infection Status
المؤلفون المشاركون
Miyazaki, Kohji
Masuda, Masanori
Tokunaga, Osamu
Takase, Yukari
Kai, Keita
Noshiro, Hirokazu
Kitahara, Kenji
Miyoshi, Atsushi
المصدر
International Journal of Hepatology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-01
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Previous studies have investigated extrahepatic multiple primary malignancy (EHPM) associated with hepatocellular carcinoma (HCC).
However, its correlation with viral infection, such as hepatitis B virus (HBV) or hepatitis C virus (HCV), has not been examined.
The aim of this study is to investigate the association between EHPM and hepatitis infection in HCC patients.
A total of 412 patients who underwent surgical resection for primary HCC were enrolled.
Viral infection was evaluated by serum HBV surface antigen (HBs Ag) and HCV antibody (HCV Ab).
Sixty-eight (16.5%) patients had one or more EHPM.
The most frequent EHPM was gastric cancer (n=32) in this cohort.
No statistical significance was observed in the distribution of viral infection and incidence of entire EHPM.
However, HCV Ab, HBs Ag, and negative status for both were correlated with the frequency of gastric (P=0.0194), urinary tract (P=0.0067), and breast cancer (P=0.0036), respectively.
Infection of Helicobacter pylori was investigated by immunohistochemistry in gastric EHPM and resulted that 20 out of 21 analyzed cases were negative for Helicobacter pylori.
Although it should be verified by well-designed large cohort studies, the current results suggested correlation between HCV infection and gastric cancer, HBV infection and urinary tract cancer and viral hepatitis-free status and breast cancer in HCC patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kai, Keita& Miyoshi, Atsushi& Kitahara, Kenji& Masuda, Masanori& Takase, Yukari& Miyazaki, Kohji…[et al.]. 2012. Analysis of Extrahepatic Multiple Primary Malignancies in Patients with Hepatocellular Carcinoma according to Viral Infection Status. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-476269
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kai, Keita…[et al.]. Analysis of Extrahepatic Multiple Primary Malignancies in Patients with Hepatocellular Carcinoma according to Viral Infection Status. International Journal of Hepatology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-476269
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kai, Keita& Miyoshi, Atsushi& Kitahara, Kenji& Masuda, Masanori& Takase, Yukari& Miyazaki, Kohji…[et al.]. Analysis of Extrahepatic Multiple Primary Malignancies in Patients with Hepatocellular Carcinoma according to Viral Infection Status. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-476269
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-476269
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر