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The Performance of Quantiferon TB Gold In-Tube as a Screening Tool in Paediatric Rheumatology prior to Initiation of Infliximab : A Single Centre's Experience
المؤلفون المشاركون
Maritsi, Despoina N.
Eleftheriou, Despina
Brogan, Paul A.
al-Obadi, Muthana
Dixon, Garth L. J.
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-08-15
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Patients with autoimmune diseases and latent tuberculosis infection (LTBI) are at risk of developing catastrophic tuberculosis disease following infliximab treatment.
Quantiferon-TB gold in-Tube (QTB) has proven a more accurate screening tool than tuberculin skin test (TST) in adult populations.
Objectives.
To assess the utility and validity of QTB in children, prior to treatment with infliximab.
Methods.
Retrospective cohort of patients started on infliximab following endorsement of QTB as a screening tool by the NICE guidelines in 2006.
Results.
Twenty three patients (12 females and 11 males) were included in the study.
A chest radiograph (CXR) and QTB was performed prior to starting infliximab.
Fourteen patients had a recorded negative TST result.
One patient had a positive QTB while two had indeterminate results.
Their CXRs were not suggestive of TB and TSTs were negative.
The patients with indeterminate results were started on infliximab and had regular clinical assessment for TB disease.
Repeat QTB was negative in one while remained indeterminate in the other.
None of our 23 patients developed TB.
Conclusion.
QTB is a useful screen tool for LTBI.
Indeterminate results warrant careful assessment and re-evaluation, but should not preclude from initiation of anti TNF treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maritsi, Despoina N.& al-Obadi, Muthana& Brogan, Paul A.& Eleftheriou, Despina& Dixon, Garth L. J.. 2011. The Performance of Quantiferon TB Gold In-Tube as a Screening Tool in Paediatric Rheumatology prior to Initiation of Infliximab : A Single Centre's Experience. ISRN Rheumatology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-476943
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maritsi, Despoina N.…[et al.]. The Performance of Quantiferon TB Gold In-Tube as a Screening Tool in Paediatric Rheumatology prior to Initiation of Infliximab : A Single Centre's Experience. ISRN Rheumatology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-476943
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maritsi, Despoina N.& al-Obadi, Muthana& Brogan, Paul A.& Eleftheriou, Despina& Dixon, Garth L. J.. The Performance of Quantiferon TB Gold In-Tube as a Screening Tool in Paediatric Rheumatology prior to Initiation of Infliximab : A Single Centre's Experience. ISRN Rheumatology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-476943
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-476943
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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