Evaluation of a Model-Based Hemodynamic Monitoring Method in a Porcine Study of Septic Shock
المؤلفون المشاركون
Lambermont, Bernard C.
Revie, James A.
Shaw, Geoffrey M.
Stevenson, David
Desaive, Thomas
Kolh, Philippe
Chase, J. Geoffrey
Pretty, Chris J.
Ghuysen, Alexandre
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-25
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Introduction.
The accuracy and clinical applicability of an improved model-based system for tracking hemodynamic changes is assessed in an animal study on septic shock.
Methods.
This study used cardiovascular measurements recorded during a porcine trial studying the efficacy of large-pore hemofiltration for treating septic shock.
Four Pietrain pigs were instrumented and induced with septic shock.
A subset of the measured data, representing clinically available measurements, was used to identify subject-specific cardiovascular models.
These models were then validated against the remaining measurements.
Results.
The system accurately matched independent measures of left and right ventricle end diastolic volumes and maximum left and right ventricular pressures to percentage errors less than 20% (except for the 95th percentile error in maximum right ventricular pressure) and all R2>0.76.
An average decrease of 42% in systemic resistance, a main cardiovascular consequence of septic shock, was observed 120 minutes after the infusion of the endotoxin, consistent with experimentally measured trends.
Moreover, modelled temporal trends in right ventricular end systolic elastance and afterload tracked changes in corresponding experimentally derived metrics.
Conclusions.
These results demonstrate that this model-based method can monitor disease-dependent changes in preload, afterload, and contractility in porcine study of septic shock.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Revie, James A.& Stevenson, David& Chase, J. Geoffrey& Pretty, Chris J.& Lambermont, Bernard C.& Ghuysen, Alexandre…[et al.]. 2013. Evaluation of a Model-Based Hemodynamic Monitoring Method in a Porcine Study of Septic Shock. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-476967
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Revie, James A.…[et al.]. Evaluation of a Model-Based Hemodynamic Monitoring Method in a Porcine Study of Septic Shock. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-17.
https://search.emarefa.net/detail/BIM-476967
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Revie, James A.& Stevenson, David& Chase, J. Geoffrey& Pretty, Chris J.& Lambermont, Bernard C.& Ghuysen, Alexandre…[et al.]. Evaluation of a Model-Based Hemodynamic Monitoring Method in a Porcine Study of Septic Shock. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-476967
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-476967
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر