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Metabonomics-Based Study of Clinical Urine Samples in Suboptimal Health with Different Syndromes
المؤلفون المشاركون
Jiang, You-Ming
Cui, Hai-Zhen
Wang, Li-Min
Li, Xiao-Hong
Wang, Shao-Xian
Zhao, Xin
Liu, Yue-Yun
Chen, Jia-Xu
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-01-17
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To explore the urinary biochemistry features of syndromes of traditional Chinese medicine (TCM) such as syndrome of stagnation of liver Qi, spleen deficiency, liver Qi stagnation, and spleen deficiency (LSSDS) in sub-optimal health status (SHS).
Methods.
12 cases for each syndrome group in SHS were selected, 12 subjects were used as a normal control group, and 1H NMR detection was, respectively, carried out, and the data was corrected by the orthogonal signal correction (OSC) and then adopted a partial least squares (PLS) method for discriminate analysis.
Results.
The OSC-PLS (ctr) analysis results of the nuclear overhauser enhancement spectroscopy (NOESY) detection indicated that the syndromes in SHS could be differentiated, and there were significant differences in the levels of metabolites of the urine samples of the four groups; the biomarkers of LSSDS in SHS were found out.
The contents of citric acid (2.54 and 2.66), trimethylamineoxide (3.26), and hippuric acid (3.98, 7.54, 7.58, 7.62, 7.66, 7.82, and 7.86) in the urine samples of LSSDS group were lower than that of the normal control group.
Conclusion.
There are differences in the 1H-NMR metabolic spectrum of the urine samples of the four groups, and the specific metabolic products of the LSSDS in SHS can be identified from metabonomics analysis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cui, Hai-Zhen& Wang, Li-Min& Zhao, Xin& Liu, Yue-Yun& Wang, Shao-Xian& Li, Xiao-Hong…[et al.]. 2013. Metabonomics-Based Study of Clinical Urine Samples in Suboptimal Health with Different Syndromes. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-477284
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cui, Hai-Zhen…[et al.]. Metabonomics-Based Study of Clinical Urine Samples in Suboptimal Health with Different Syndromes. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-477284
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cui, Hai-Zhen& Wang, Li-Min& Zhao, Xin& Liu, Yue-Yun& Wang, Shao-Xian& Li, Xiao-Hong…[et al.]. Metabonomics-Based Study of Clinical Urine Samples in Suboptimal Health with Different Syndromes. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-477284
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-477284
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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