Inflammatory Reaction as Determinant of Foreign Body Reaction Is an Early and Susceptible Event after Mesh Implantation
المؤلفون المشاركون
Georgas, Evangelos
Otto, Stephan
Gerullis, Holger
Barski, Dimitri
Ysebaert, Dirk
Otto, Thomas
Eimer, Christoph
Ramon, Albert
Klosterhalfen, Bernd
Borós, Mihaly
Arndt, Christian
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
To investigate and relate the ultrashort-term and long-term courses of determinants for foreign body reaction as biocompatibility predictors for meshes in an animal model.
Materials and Methods.
Three different meshes (TVT, UltraPro, and PVDF) were implanted in sheep.
Native and plasma coated meshes were placed bilaterally: (a) interaperitoneally, (b) as fascia onlay, and (c) as muscle onlay (fascia sublay).
At 5 min, 20 min, 60 min, and 120 min meshes were explanted and histochemically investigated for inflammatory infiltrate, macrophage infiltration, vessel formation, myofibroblast invasion, and connective tissue accumulation.
The results were related to long-term values over 24 months.
Results.
Macrophage invasion reached highest extents with up to 60% in short-term and decreased within 24 months to about 30%.
Inflammatory infiltrate increased within the first 2 hours, the reached levels and the different extents and ranking among the investigated meshes remained stable during long-term follow up.
For myofibroblasts, connective tissue, and CD31+ cells, no activity was detected during the first 120 min.
Conclusion.
The local inflammatory reaction is an early and susceptible event after mesh implantation.
It cannot be influenced by prior plasma coating and does not depend on the localisation of implantation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gerullis, Holger& Georgas, Evangelos& Borós, Mihaly& Klosterhalfen, Bernd& Eimer, Christoph& Arndt, Christian…[et al.]. 2014. Inflammatory Reaction as Determinant of Foreign Body Reaction Is an Early and Susceptible Event after Mesh Implantation. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-477445
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gerullis, Holger…[et al.]. Inflammatory Reaction as Determinant of Foreign Body Reaction Is an Early and Susceptible Event after Mesh Implantation. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-477445
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gerullis, Holger& Georgas, Evangelos& Borós, Mihaly& Klosterhalfen, Bernd& Eimer, Christoph& Arndt, Christian…[et al.]. Inflammatory Reaction as Determinant of Foreign Body Reaction Is an Early and Susceptible Event after Mesh Implantation. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-477445
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-477445
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر