New Di- and Triorganotin(IV) Tyrosylalaninates as Models for Metal—Protein Interactions : Synthesis, Structural Characterization, and Potentiometric Studies of Tyrosylalanine, Glycyltyrosine, and Glycylisoleucine with Di- and Trimethyltin(IV) Moieties in Aqueous Medium
المؤلفون المشاركون
Song, Xueqing
Sulaxna,
Nath, Mala
Eng, George
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-15
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Di- and triorganotin(IV) derivatives of tyrosylalanine (H2Tyr-Ala) with general formula R2Sn(Tyr-Ala) (where R = Me, n-Bu, n-Oct, and Ph) and R3Sn(HTyr-Ala) (where R = Me and Ph) have been synthesized and structurally characterized in the solid state as well as in solution on the basis of various spectroscopic techniques, namely.
FT-IR, multinuclear (1H, 13C and 119Sn) NMR and 119Sn Mössbauer.
These investigations suggest that tyrosylalanine in R2Sn(Tyr-Ala) acts as dianionic tridentate ligand coordinating through carboxylate oxygen [–C(O)O−], amino (–NH2), and (CO)Npeptide- nitrogen, while in the case of R3Sn(HTyr-Ala), the ligand acts as monoanionic bidentate coordinating through –C(O)O− and –NH2, and the polyhedron around tin in R2Sn(Tyr-Ala) and R3Sn(HTyr-Ala) is a distorted trigonal-bipyramidal.
Equilibrium (pH-metric) studies of the interaction of Me2Sn(IV)2+ and Me3Sn(IV)+ with dipeptides namely, tyrosylalanine (H2Tyr-Ala), glycyltyrosine (H2Gly-Tyr), and glycylisoleucine (H2Gly-Ile), in aqueous solution (I = 0.1 M KNO3, 298 K) have also been carried out.
The concentration distribution of the various complex species in solution has been evaluated as a function of pH.
It has been found that in these dipeptides, [–C(O)O−, N−, NH2] coordinated complexes are dominant in the neutral pH range with a trigonal-bipyramidal structure.
The complex species formed are water soluble in the pH range 2.7–10.5.
In all of the studied systems, no polymeric species have been detected in the experimental pH range.
Beyond pH 8.0, significant amounts of hydroxo species, namely.
Me3Sn(OH) and Me2Sn(OH)2, are formed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nath, Mala& Sulaxna, & Song, Xueqing& Eng, George. 2012. New Di- and Triorganotin(IV) Tyrosylalaninates as Models for Metal—Protein Interactions : Synthesis, Structural Characterization, and Potentiometric Studies of Tyrosylalanine, Glycyltyrosine, and Glycylisoleucine with Di- and Trimethyltin(IV) Moieties in Aqueous Medium. ISRN Spectroscopy،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-478019
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nath, Mala…[et al.]. New Di- and Triorganotin(IV) Tyrosylalaninates as Models for Metal—Protein Interactions : Synthesis, Structural Characterization, and Potentiometric Studies of Tyrosylalanine, Glycyltyrosine, and Glycylisoleucine with Di- and Trimethyltin(IV) Moieties in Aqueous Medium. ISRN Spectroscopy No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-478019
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nath, Mala& Sulaxna, & Song, Xueqing& Eng, George. New Di- and Triorganotin(IV) Tyrosylalaninates as Models for Metal—Protein Interactions : Synthesis, Structural Characterization, and Potentiometric Studies of Tyrosylalanine, Glycyltyrosine, and Glycylisoleucine with Di- and Trimethyltin(IV) Moieties in Aqueous Medium. ISRN Spectroscopy. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-478019
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-478019
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر