Evaluation of Aromatic Plants and Compounds Used to Fight Multidrug Resistant Infections
المؤلفون المشاركون
Perumal Samy, Ramar
Manikandan, Jayapal
al-Qahtani, Mohammed
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-08
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Traditional medicine plays a vital role for primary health care in India, where it is widely practiced to treat various ailments.
Among those obtained from the healers, 78 medicinal plants were scientifically evaluated for antibacterial activity.
Methanol extract of plants (100 μg of residue) was tested against the multidrug resistant (MDR) Gram-negative and Gram-positive bacteria.
Forty-seven plants showed strong activity against Burkholderia pseudomallei (strain TES and KHW) and Staphylococcus aureus, of which Tragia involucrata L., Citrus acida Roxb.
Hook.f., and Aegle marmelos (L.) Correa ex Roxb.
showed powerful inhibition of bacteria.
Eighteen plants displayed only a moderate effect, while six plants failed to provide any evidence of inhibition against the tested bacteria.
Purified compounds showed higher antimicrobial activity than crude extracts.
The compounds showed less toxic effect to the human skin fibroblasts (HEPK) cells than their corresponding aromatic fractions.
Phytochemical screening indicates that the presence of various secondary metabolites may be responsible for this activity.
Most of the plant extracts contained high levels of phenolic or polyphenolic compounds and exhibited activity against MDR pathogens.
In conclusion, plants are promising agents that deserve further exploration.
Lead molecules available from such extracts may serve as potential antimicrobial agents for future drug development to combat diseases caused by the MDR bacterial strains as reported in this study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Perumal Samy, Ramar& Manikandan, Jayapal& al-Qahtani, Mohammed. 2013. Evaluation of Aromatic Plants and Compounds Used to Fight Multidrug Resistant Infections. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-478642
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Perumal Samy, Ramar…[et al.]. Evaluation of Aromatic Plants and Compounds Used to Fight Multidrug Resistant Infections. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-17.
https://search.emarefa.net/detail/BIM-478642
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Perumal Samy, Ramar& Manikandan, Jayapal& al-Qahtani, Mohammed. Evaluation of Aromatic Plants and Compounds Used to Fight Multidrug Resistant Infections. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-478642
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-478642
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر