Endothelial Activation Microparticles and Inflammation Status Improve with Exercise Training in African Americans
المؤلفون المشاركون
Lee, Hojun
Veerabhadrappa, Praveen
Williamson, Sheara T.
Kashem, Mohammed A.
Kretzschmar, Jan
Crabbe, Deborah L.
Thakkar, Sunny R.
Grimm, Heather
Babbitt, Dianne M.
Brown, Michael D.
Diaz, Keith M.
Sturgeon, Kathleen M.
Feairheller, Deborah L.
Ling, Chenyi
Perkins, Amanda M.
المصدر
International Journal of Hypertension
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation.
The purpose of this study was to determine the effects of a 6-month aerobic exercise training (AEXT) intervention on the inflammatory biomarkers interleukin-10 (IL-10), interleukin-6 (IL-6), and endothelial microparticle (EMP) CD62E+ and endothelial function assessed by flow-mediated dilation (FMD) in African Americans.
A secondary purpose was to evaluate whether changes in IL-10, IL-6, or CD62E+ EMPs predicted the change in FMD following the 6-month AEXT intervention.
A pre-post design was employed with baseline evaluation including office blood pressure, FMD, fasting blood sampling, and graded exercise testing.
Participants engaged in 6 months of AEXT.
Following the AEXT intervention, all baseline tests were repeated.
FMD significantly increased, CD62E+ EMPs and IL-6 significantly decreased, and IL-10 increased but not significantly following AEXT.
Changes in inflammatory biomarkers did not significantly predict the change in FMD.
The change in VO2 max significantly predicted the change in IL-10.
Based on these results, AEXT may be a viable, nonpharmacological method to improve inflammation status and endothelial function and thereby contribute to risk reduction for cardiovascular disease in African Americans.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Babbitt, Dianne M.& Diaz, Keith M.& Feairheller, Deborah L.& Sturgeon, Kathleen M.& Perkins, Amanda M.& Veerabhadrappa, Praveen…[et al.]. 2013. Endothelial Activation Microparticles and Inflammation Status Improve with Exercise Training in African Americans. International Journal of Hypertension،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-479670
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Babbitt, Dianne M.…[et al.]. Endothelial Activation Microparticles and Inflammation Status Improve with Exercise Training in African Americans. International Journal of Hypertension No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-479670
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Babbitt, Dianne M.& Diaz, Keith M.& Feairheller, Deborah L.& Sturgeon, Kathleen M.& Perkins, Amanda M.& Veerabhadrappa, Praveen…[et al.]. Endothelial Activation Microparticles and Inflammation Status Improve with Exercise Training in African Americans. International Journal of Hypertension. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-479670
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-479670
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر