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Assessment of Lipocalin 2, Clusterin, Soluble Tumor Necrosis Factor Receptor-1, Interleukin-6, Homocysteine, and Uric Acid Levels in Patients with Psoriasis
المؤلفون المشاركون
Kurtipek, Gulcan Saylam
Ataseven, Arzu
Ozturk, Perihan
Kesli, Recep
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Chronic inflammation may play a role in psoriasis pathogenesis.
Lipocalin 2, clusterin, soluble tumor necrosis factor receptor-1 (sTNFR-1), interleukin-6, homocysteine, and uric acid are inflammatory and/or biochemical markers.
However, both the roles of these markers and the pathogenesis of psoriasis are unknown.
Objective.
The aim of this study was to investigate serum levels of lipocalin 2, clusterin, sTNFR-1, interleukin-6, homocysteine, and uric acid in patients and controls groups.
Methods.
Fifty-six patients with psoriasis and 33 healthy controls were included in the study.
Serum concentrations of the markers were evaluated by ELISA.
The Psoriasis Area and Severity Index (PASI) was evaluated in all psoriasis patients.
Body mass index (BMI) was calculated by dividing weight (kg) by height (m) squared.
Results.
The serum value of lipocalin and sTNFR-1 were significantly higher in psoriasis patients than in controls (resp., P<0.001, P<0.05).
The others showed no significant differences between psoriasis and the control groups (all of them P>0.05).
The mean PASI score in the patient group was 8.3±6.5.
Conclusions.
These findings suggest that lipocalin 2 and sTNFR-1 might play a role in the pathogenesis of psoriasis and can be used as markers of the disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ataseven, Arzu& Kesli, Recep& Kurtipek, Gulcan Saylam& Ozturk, Perihan. 2014. Assessment of Lipocalin 2, Clusterin, Soluble Tumor Necrosis Factor Receptor-1, Interleukin-6, Homocysteine, and Uric Acid Levels in Patients with Psoriasis. Disease Markers،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-480025
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ataseven, Arzu…[et al.]. Assessment of Lipocalin 2, Clusterin, Soluble Tumor Necrosis Factor Receptor-1, Interleukin-6, Homocysteine, and Uric Acid Levels in Patients with Psoriasis. Disease Markers No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-480025
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ataseven, Arzu& Kesli, Recep& Kurtipek, Gulcan Saylam& Ozturk, Perihan. Assessment of Lipocalin 2, Clusterin, Soluble Tumor Necrosis Factor Receptor-1, Interleukin-6, Homocysteine, and Uric Acid Levels in Patients with Psoriasis. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-480025
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480025
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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