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Inactivation of the Catalytic Subunit of cAMP-Dependent Protein Kinase A Causes Delayed Appressorium Formation and Reduced Pathogenicity of Colletotrichum gloeosporioides
المؤلفون المشاركون
Abdul Murad, Abdul Munir
Abu Bakar, Farah Diba
Priyatno, Tri Puji
Kamaruddin, Nurhaida
Mahadi, Nor Muhammad
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-01
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
The cyclic AMP- (cAMP-) dependent protein kinase A signaling pathway is one of the major signaling pathways responsible for regulation of the morphogenesis and pathogenesis of several pathogenic fungi.
To evaluate the role of this pathway in the plant pathogenic fungus, Colletotrichum gloeosporioides, the gene encoding the catalytic subunit of cAMP-dependent protein kinase A, CgPKAC, was cloned, inactivated, and the mutant was analyzed.
Analysis of the Cgpkac mutant generated via gene replacement showed that the mutants were able to form appressoria; however, their formation was delayed compared to the wild type.
In addition, the mutant conidia underwent bipolar germination after appressoria formation, but no appressoria were generated from the second germ tube.
The mutants also showed reduced ability to adhere to a hydrophobic surface and to degrade lipids localized in the appressoria.
Based on the number of lesions produced during a pathogenicity test, the mutant’s ability to cause disease in healthy mango fruits was reduced, which may be due to failure to penetrate into the fruit.
These findings indicate that cAMP-dependent protein kinase A has an important role in regulating morphogenesis and is required for pathogenicity of C.
gloeosporioides.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Priyatno, Tri Puji& Abu Bakar, Farah Diba& Kamaruddin, Nurhaida& Mahadi, Nor Muhammad& Abdul Murad, Abdul Munir. 2012. Inactivation of the Catalytic Subunit of cAMP-Dependent Protein Kinase A Causes Delayed Appressorium Formation and Reduced Pathogenicity of Colletotrichum gloeosporioides. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-480319
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Priyatno, Tri Puji…[et al.]. Inactivation of the Catalytic Subunit of cAMP-Dependent Protein Kinase A Causes Delayed Appressorium Formation and Reduced Pathogenicity of Colletotrichum gloeosporioides. The Scientific World Journal No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-480319
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Priyatno, Tri Puji& Abu Bakar, Farah Diba& Kamaruddin, Nurhaida& Mahadi, Nor Muhammad& Abdul Murad, Abdul Munir. Inactivation of the Catalytic Subunit of cAMP-Dependent Protein Kinase A Causes Delayed Appressorium Formation and Reduced Pathogenicity of Colletotrichum gloeosporioides. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-480319
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480319
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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