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Florbetaben PET in the Early Diagnosis of Alzheimer's Disease : A Discrete Event Simulation to Explore Its Potential Value and Key Data Gaps
المؤلفون المشاركون
Blankenburg, Michael
Lanes, Stephan
Getsios, Denis
Altincatal, Arman
Lawler, Elizabeth V.
Cho, Kelly
Guo, Shien
Hernandez, Luis
المصدر
International Journal of Alzheimer's Disease
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-26
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
The growing understanding of the use of biomarkers in Alzheimer's disease (AD) may enable physicians to make more accurate and timely diagnoses.
Florbetaben, a beta-amyloid tracer used with positron emission tomography (PET), is one of these diagnostic biomarkers.
This analysis was undertaken to explore the potential value of florbetaben PET in the diagnosis of AD among patients with suspected dementia and to identify key data that are needed to further substantiate its value.
A discrete event simulation was developed to conduct exploratory analyses from both US payer and societal perspectives.
The model simulates the lifetime course of disease progression for individuals, evaluating the impact of their patient management from initial diagnostic work-up to final diagnosis.
Model inputs were obtained from specific analyses of a large longitudinal dataset from the New England Veterans Healthcare System and supplemented with data from public data sources and assumptions.
The analyses indicate that florbetaben PET has the potential to improve patient outcomes and reduce costs under certain scenarios.
Key data on the use of florbetaben PET, such as its influence on time to confirmation of final diagnosis, treatment uptake, and treatment persistency, are unavailable and would be required to confirm its value.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guo, Shien& Getsios, Denis& Hernandez, Luis& Cho, Kelly& Lawler, Elizabeth V.& Altincatal, Arman…[et al.]. 2012. Florbetaben PET in the Early Diagnosis of Alzheimer's Disease : A Discrete Event Simulation to Explore Its Potential Value and Key Data Gaps. International Journal of Alzheimer's Disease،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-480524
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guo, Shien…[et al.]. Florbetaben PET in the Early Diagnosis of Alzheimer's Disease : A Discrete Event Simulation to Explore Its Potential Value and Key Data Gaps. International Journal of Alzheimer's Disease No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-480524
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guo, Shien& Getsios, Denis& Hernandez, Luis& Cho, Kelly& Lawler, Elizabeth V.& Altincatal, Arman…[et al.]. Florbetaben PET in the Early Diagnosis of Alzheimer's Disease : A Discrete Event Simulation to Explore Its Potential Value and Key Data Gaps. International Journal of Alzheimer's Disease. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-480524
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480524
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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