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Synthesis, Characterization, and Biological Evaluation of Some 3d-Metal Complexes of Schiff Base Derived from Xipamide Drug
المؤلفون المشاركون
Ghosh, Suparna
Bhattacharya, Mamta
Malik, Suman
Singh, Archana
Jain, Bharti
المصدر
International Journal of Inorganic Chemistry
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The present paper deals with the synthesis and characterization of metal complexes of Schiff base derived from xipamide, a diuretic drug.
The bidentate ligand is derived from the inserted condensation of 5-aminosulfonyl-4-chloro-N-2,6-dimethyl phenyl-2-hydroxybenzamide (Xipamide) with salicylaldehyde in a 1 : 1 molar ratio.
Using this bidentate ligand, complexes of Hg(II), Zn(II), and VO(IV) with general formula ML2 have been synthesized.
The synthesized complexes were characterized by several techniques using molar conductance, elemental analysis, magnetic susceptibility, FT-IR spectroscopy, electronic spectra, mass spectra, and particle size analysis.
The elemental analysis data suggest the stoichiometry to be 1 : 2 [M : L].
All the complexes are nonelectrolytic in nature as suggested by molar conductance measurements.
Infrared spectral data indicate the coordination between the ligand and the central metal ion through deprotonated phenolic oxygen and azomethine nitrogen atoms.
Spectral studies suggest tetrahedral geometry for Hg(II), Zn(II) complexes, and square pyramidal geometry for VO(IV) complex.
The pure drug, synthesized ligand, and metal complexes were screened for their antifungal activities against Aspergillus niger and Aspergillus flavus.
The ligand and its Hg(II) and VO(IV) complexes were screened for their diuretic activity too.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Malik, Suman& Ghosh, Suparna& Jain, Bharti& Singh, Archana& Bhattacharya, Mamta. 2013. Synthesis, Characterization, and Biological Evaluation of Some 3d-Metal Complexes of Schiff Base Derived from Xipamide Drug. International Journal of Inorganic Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-480712
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Malik, Suman…[et al.]. Synthesis, Characterization, and Biological Evaluation of Some 3d-Metal Complexes of Schiff Base Derived from Xipamide Drug. International Journal of Inorganic Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-480712
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Malik, Suman& Ghosh, Suparna& Jain, Bharti& Singh, Archana& Bhattacharya, Mamta. Synthesis, Characterization, and Biological Evaluation of Some 3d-Metal Complexes of Schiff Base Derived from Xipamide Drug. International Journal of Inorganic Chemistry. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-480712
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480712
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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