Innervation of a Prefabricated Flap : A New Experimental Model
المؤلفون المشاركون
Cuccia, Giuseppe
Romeo, Marco
Geuna, Stefano
Hontanilla, Bernardo
Raimondo, Stefania
Qiu, Shan Shan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Flap innervation by neoaxonogenesis is a promising field of investigation.
The authors evaluated the possibility of innervating an acellular collagen scaffold as component of a potential prefabricated flap.
Materials and Methods.
Collagen matrix sheets were implanted around the femoral bundle of a murine model to produce two flaps on proximal and distal nerve stumps based on a flow-through model.
After thirty days, nerve regeneration and integration into the collagen matrix were evaluated.
The specimens were microscopically analyzed to study Schwann cell colonization and axonal integration with the matrix.
Axonal count and density were assessed and statistically evaluated.
Results.
Qualitative structural and ultrastructural evaluation indicated integration, with axonal fibers merged within the collagen matrix, along with a newly formed vascular network on the proximal flap.
Wallerian degeneration occurred inside the distal chamber.
Axonal count and density did not show statistically significant differences between the nerve inside the proximal flap and the control side.
Conclusions.
Innervation of an acellular matrix can be obtained by direct nerve stump implantation.
The flow-through system was relatively easy to build and reliable to provide adequate blood supply.
The collagen scaffold may be a promising support or further studies of preinnervated microsurgical flaps.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Romeo, Marco& Cuccia, Giuseppe& Qiu, Shan Shan& Raimondo, Stefania& Geuna, Stefano& Hontanilla, Bernardo. 2014. Innervation of a Prefabricated Flap : A New Experimental Model. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-480714
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Romeo, Marco…[et al.]. Innervation of a Prefabricated Flap : A New Experimental Model. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-480714
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Romeo, Marco& Cuccia, Giuseppe& Qiu, Shan Shan& Raimondo, Stefania& Geuna, Stefano& Hontanilla, Bernardo. Innervation of a Prefabricated Flap : A New Experimental Model. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-480714
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480714
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر