Investigational Paradigms in Downscoring and Upscoring DCIS : Surgical Management Review
المؤلفون المشاركون
Orsaria, Paolo
Buonomo, Oreste Claudio
Venditti, D.
Petrella, Giuseppe
Granai, Alessandra Vittoria
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-16
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Counseling patients with DCIS in a rational manner can be extremely difficult when the range of treatment criteria results in diverse and confusing clinical recommendations.
Surgeons need tools that quantify measurable prognostic factors to be used in conjunction with clinical experience for the complex decision-making process.
Combination of statistically significant tumor recurrence predictors and lesion parameters obtained after initial excision suggests that patients with DCIS can be stratified into specific subsets allowing a scientifically based discussion.
The goal is to choose the treatment regimen that will significantly benefit each patient group without subjecting the patients to unnecessary risks.
Exploring the effectiveness of complete excision may offer a starting place in a new way of reasoning and conceiving surgical modalities in terms of “downscoring” or “upscoring” patient risk, perhaps changing clinical approach.
Reexcison may lower the specific subsets' score and improve local recurrence-free survival also by revealing a larger tumor size, a higher nuclear grade, or an involved margin and so suggesting the best management.
It seems, that the key could be identifying significant relapse predictive factors, according to validated risk investigation models, whose value is modifiable by the surgical approach which avails of different diagnostic and therapeutic potentials to be optimal.
Certainly DCIS clinical question cannot have a single curative mode due to heterogeneity of pathological lesions and histologic classification.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Orsaria, Paolo& Granai, Alessandra Vittoria& Venditti, D.& Petrella, Giuseppe& Buonomo, Oreste Claudio. 2012. Investigational Paradigms in Downscoring and Upscoring DCIS : Surgical Management Review. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-480775
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Orsaria, Paolo…[et al.]. Investigational Paradigms in Downscoring and Upscoring DCIS : Surgical Management Review. International Journal of Surgical Oncology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-480775
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Orsaria, Paolo& Granai, Alessandra Vittoria& Venditti, D.& Petrella, Giuseppe& Buonomo, Oreste Claudio. Investigational Paradigms in Downscoring and Upscoring DCIS : Surgical Management Review. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-480775
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480775
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر