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Neurodegenerative Diseases : Multifactorial Conformational Diseases and Their Therapeutic Interventions
المؤلفون المشاركون
Haque, Ejazul
Sheikh, Saba
Mir, Snober S.
Safia,
المصدر
Journal of Neurodegenerative Diseases
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-30
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Neurodegenerative diseases are multifactorial debilitating disorders of the nervous system that affect approximately 30 millionindividuals worldwide.
Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis diseases are the consequence of misfolding and dysfunctional trafficking of proteins.
Beside that, mitochondrial dysfunction, oxidative stress, and/or environmental factors strongly associated with age have also been implicated in causing neurodegeneration.
After years of intensive research, considerable evidence has accumulated that demonstrates an important role of these factors in the etiology of common neurodegenerative diseases.
Despite the extensive efforts that have attempted to define the molecular mechanisms underlying neurodegeneration, many aspects of these pathologies remain elusive.
However, in order to explore the therapeutic interventions directed towards treatment of neurodegenerative diseases, neuroscientists are now fully exploiting the data obtained from studies of these basic mechanisms that have gone awry.
The novelty of these mechanisms represents a challenge to the identification of viable drug targets and biomarkers for early diagnosis of the diseases.
In this paper, we are reviewing various aspects associated with the disease and the recent trends that may have an application for the treatment of the neurodegenerative disorders.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sheikh, Saba& Safia, & Haque, Ejazul& Mir, Snober S.. 2012. Neurodegenerative Diseases : Multifactorial Conformational Diseases and Their Therapeutic Interventions. Journal of Neurodegenerative Diseases،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-481057
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sheikh, Saba…[et al.]. Neurodegenerative Diseases : Multifactorial Conformational Diseases and Their Therapeutic Interventions. Journal of Neurodegenerative Diseases No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-481057
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sheikh, Saba& Safia, & Haque, Ejazul& Mir, Snober S.. Neurodegenerative Diseases : Multifactorial Conformational Diseases and Their Therapeutic Interventions. Journal of Neurodegenerative Diseases. 2012. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-481057
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481057
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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