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Twenty Years of Experience with the Preoperative Diagnosis of Medullary Cancer in a Moderately Iodine-Deficient Region
المؤلفون المشاركون
Lukacs Toth, Gyula
Nagy, Dezso
Gal, Istvan
Solymosi, Tamas
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
There is a current debate in the medical literature about plasma calcitonin screening in patients with nodular goiter (NG).
We decided on analyzing our 20-year experience with patients in an iodine-deficient region (ID).
Patients and Methods.
22,857 consecutive patients with NG underwent ultrasonography and aspiration cytology (FNAC).
If FNAC raised suspicion of medullary cancer (MTC), the serum calcitonin was measured.
Results.
4,601 patients underwent surgery; there were 23 patients among them who had MTC (0.1% prevalence).
Significantly more MTC cases were diagnosed cytologically in the second decade than in the first: 11/12 and 6/11, respectively.
The frozen section was of help in 2 cases out of 3.
Two patients suffered from a 3-year delay in proper therapy, and reoperation was necessary in 1 case.
FNAC raised the suspicion of MTC in 20 cases that were later histologically verified and did not present MTC.
The diagnostic accuracy of FNAC in diagnosing MTC was 99.2%.
Two false-positive serum calcitonin tests (one of them in a hemodialyzed patient) and one false-negative serum calcitonin test occurred in 40 cases.
Conclusion.
Regarding the low prevalence of MTC in ID regions, calcitonin screening of all NG patients does not only appear superfluously but may have more disadvantages than advantages.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Solymosi, Tamas& Lukacs Toth, Gyula& Nagy, Dezso& Gal, Istvan. 2013. Twenty Years of Experience with the Preoperative Diagnosis of Medullary Cancer in a Moderately Iodine-Deficient Region. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-481684
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Solymosi, Tamas…[et al.]. Twenty Years of Experience with the Preoperative Diagnosis of Medullary Cancer in a Moderately Iodine-Deficient Region. International Journal of Endocrinology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-481684
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Solymosi, Tamas& Lukacs Toth, Gyula& Nagy, Dezso& Gal, Istvan. Twenty Years of Experience with the Preoperative Diagnosis of Medullary Cancer in a Moderately Iodine-Deficient Region. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-481684
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481684
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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