Brain Levels of Catalase Remain Constant through Strain, Developmental, and Chronic Alcohol Challenges
المؤلفون المشاركون
Rhoads, Dennis E.
Contreras, Cherly
Fathalla, Salma
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Catalase (EC 1.11.1.6) oxidizes ethanol to acetaldehyde within the brain and variations in catalase activity may underlie some consequences of ethanol consumption.
The goals of this study were to measure catalase activity in subcellular fractions from rat brain and to compare the levels of this enzyme in several important settings.
In the first series of studies, levels of catalase were compared between juvenile and adult rats and between the Long-Evans (LE) and Sprague-Dawley (SD) strains.
Levels of catalase appear to have achieved the adult level by the preadolescent period defined by postnatal age (P, days) P25–P28, and there were no differences between strains at the developmental stages tested.
Thus, variation in catalase activity is unlikely to be responsible for differences in how adolescent and adult rats respond to ethanol.
In the second series of studies, periadolescent and adult rats were administered ethanol chronically through an ethanol-containing liquid diet.
Diet consumption and blood ethanol concentrations were significantly higher for periadolescent rats.
Catalase activities remained unchanged following ethanol consumption, with no significant differences within or between strains.
Thus, the brain showed no apparent adaptive changes in levels of catalase, even when faced with the high levels of ethanol consumption characteristic of periadolescent rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rhoads, Dennis E.& Contreras, Cherly& Fathalla, Salma. 2012. Brain Levels of Catalase Remain Constant through Strain, Developmental, and Chronic Alcohol Challenges. Enzyme Research،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481822
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rhoads, Dennis E.…[et al.]. Brain Levels of Catalase Remain Constant through Strain, Developmental, and Chronic Alcohol Challenges. Enzyme Research No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-481822
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rhoads, Dennis E.& Contreras, Cherly& Fathalla, Salma. Brain Levels of Catalase Remain Constant through Strain, Developmental, and Chronic Alcohol Challenges. Enzyme Research. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481822
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481822
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر