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The Effect of Beta-Aminopropionitrile and Prednisolone on the Prevention of Fibrosis in Alkali Esophageal Burns : An Experimental Study
المؤلفون المشاركون
Eser, Mediha
Yanar, Hakan Teoman
Gulcin, Hepgul E.
Agcaoglu, Orhan
Dogan, Halil
Ayvaci, Baris Murat
Celikmen, Ferudun
Aciksari, Kurtulus
Gunay, Kayihan
Topacoglu, Hakan
Yanar, Fatih
Ertekin, Cemalettin
Tanriverdi, Gamze
Ozucelik, Dogac Niyazi
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
The aim of this study was to investigate the efficacy of beta-aminopropionitrile (BAPN) and prednisolone on the prevention of esophageal damage and stricture formation after caustic esophageal burn.
Method.
Twenty-eight rats were divided into four equal groups.
In groups 1, 2, and 3, caustic esophageal burns were generated by applying NaOH to the 1.5 cm segment of the abdominal esophagus.
Group 4 was for the sham.
Normal saline to group 1, BAPN to group 2, and prednisolone to group 3 were administered intraperitoneally as a single daily dose.
Results.
Treatment with BAPN decreased the stenosis index (SI) and histopathologic damage score (HDS) seen in caustic esophageal burn rats.
The SI in group 4 was significantly lower compared with groups 1, 2, and 3.
Group 2 had the minimum SI value in corrosive burn groups.
The differences related to SI between groups 1, 2, and 3 were not statistically significant.
The HDS was significantly lower in group 4 compared with groups 1, 2, and 3.
The HDS in group 2 was significantly lower compared with groups 1 and 3.
Conclusion.
This study demonstrated that BAPN was able to decrease the development of stenosis and tissue damage better than prednisolone.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aciksari, Kurtulus& Yanar, Hakan Teoman& Gulcin, Hepgul E.& Ozucelik, Dogac Niyazi& Yanar, Fatih& Agcaoglu, Orhan…[et al.]. 2013. The Effect of Beta-Aminopropionitrile and Prednisolone on the Prevention of Fibrosis in Alkali Esophageal Burns : An Experimental Study. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-481943
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aciksari, Kurtulus…[et al.]. The Effect of Beta-Aminopropionitrile and Prednisolone on the Prevention of Fibrosis in Alkali Esophageal Burns : An Experimental Study. Gastroenterology Research and Practice No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-481943
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aciksari, Kurtulus& Yanar, Hakan Teoman& Gulcin, Hepgul E.& Ozucelik, Dogac Niyazi& Yanar, Fatih& Agcaoglu, Orhan…[et al.]. The Effect of Beta-Aminopropionitrile and Prednisolone on the Prevention of Fibrosis in Alkali Esophageal Burns : An Experimental Study. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-481943
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481943
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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