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Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders
المؤلفون المشاركون
Crook, Tina A.
Melnyk, Stepan
Starrett, William
Pauly, Margaret
Pavliv, Oleksandra
James, S. Jill
Hamlin, Joanna C.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-16
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Abnormalities in folate-dependent one-carbon metabolism have been reported in many children with autism.
Because inadequate choline and betaine can negatively affect folate metabolism and in turn downstream methylation and antioxidant capacity, we sought to determine whether dietary intake of choline and betaine in children with autism was adequate to meet nutritional needs based on national recommendations.
Three-day food records were analyzed for 288 children with autism (ASDs) who participated in the national Autism Intervention Research Network for Physical Health (AIR-P) Study on Diet and Nutrition in children with autism.
Plasma concentrations of choline and betaine were measured in a subgroup of 35 children with ASDs and 32 age-matched control children.
The results indicated that 60–93% of children with ASDs were consuming less than the recommended Adequate Intake (AI) for choline.
Strong positive correlations were found between dietary intake and plasma concentrations of choline and betaine in autistic children as well as lower plasma concentrations compared to the control group.
We conclude that choline and betaine intake is inadequate in a significant subgroup of children with ASDs and is reflected in lower plasma levels.
Inadequate intake of choline and betaine may contribute to the metabolic abnormalities observed in many children with autism and warrants attention in nutritional counseling.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hamlin, Joanna C.& Pauly, Margaret& Melnyk, Stepan& Pavliv, Oleksandra& Starrett, William& Crook, Tina A.…[et al.]. 2013. Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders. Autism Research and Treatment،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-482224
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hamlin, Joanna C.…[et al.]. Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders. Autism Research and Treatment No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-482224
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hamlin, Joanna C.& Pauly, Margaret& Melnyk, Stepan& Pavliv, Oleksandra& Starrett, William& Crook, Tina A.…[et al.]. Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders. Autism Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-482224
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-482224
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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