Elevated Serum Carboxymethyl-Lysine, an Advanced Glycation End Product, Predicts Severe Walking Disability in Older Women : The Women's Health and Aging Study I
المؤلفون المشاركون
Varadhan, Ravi
Fried, Linda P.
Sun, Kai
Semba, Richard D.
Schaumberg, Debra A.
Ferrucci, Luigi
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Advanced glycation end products (AGEs) have been implicated in the pathogenesis of sarcopenia.
Our aim was to characterize the relationship between serum carboxymethyl-lysine (CML), a major circulating AGE, and incident severe walking disability (inability to walk or walking speed <0.4 m/sec) over 30 months of followup in 394 moderately to severely disabled women, ≥65 years, living in the community in Baltimore, Maryland (the Women’s Health and Aging Study I).
During followup, 154 (26.4%) women developed severe walking disability, and 23 women died.
Women in the highest quartile of serum CML had increased risk of developing of severe walking disability in a multivariate Cox proportional hazards model, adjusting for age and other potential confounders.
Women with elevated serum CML are at an increased risk of developing severe walking disability.
AGEs are a potentially modifiable risk factor.
Further work is needed to establish a causal relationship between AGEs and walking disability.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Kai& Semba, Richard D.& Fried, Linda P.& Schaumberg, Debra A.& Ferrucci, Luigi& Varadhan, Ravi. 2012. Elevated Serum Carboxymethyl-Lysine, an Advanced Glycation End Product, Predicts Severe Walking Disability in Older Women : The Women's Health and Aging Study I. Journal of Aging Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-482938
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Kai…[et al.]. Elevated Serum Carboxymethyl-Lysine, an Advanced Glycation End Product, Predicts Severe Walking Disability in Older Women : The Women's Health and Aging Study I. Journal of Aging Research No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-482938
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Kai& Semba, Richard D.& Fried, Linda P.& Schaumberg, Debra A.& Ferrucci, Luigi& Varadhan, Ravi. Elevated Serum Carboxymethyl-Lysine, an Advanced Glycation End Product, Predicts Severe Walking Disability in Older Women : The Women's Health and Aging Study I. Journal of Aging Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-482938
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-482938
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر