In Critically Ill Patients, Serum Procalcitonin Is More Useful in Differentiating between Sepsis and SIRS than CRP, Il-6, or LBP
المؤلفون المشاركون
Droog, Wouter
Batstra, Manou
Meynaar, Iwan A.
Vreede, Rolf
Herbrink, Paul
المصدر
Critical Care Research and Practice
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-05-15
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
We studied the usefulness of serum procalcitonin (PCT), interleukin-6 (IL-6), lipopolysaccharide binding protein (LBP) levels and C-reactive protein (CRP) levels, in differentiating between systemic inflammatory response syndrome (SIRS) and sepsis in critically ill patients.
Methods.
In this single centre prospective observational study we included all consecutive patients admitted with SIRS or sepsis to the ICU.
Blood samples for measuring CRP, PCT, IL-6 and LBP were taken every day until ICU discharge.
Results.
A total of 76 patients were included, 32 with sepsis and 44 with SIRS.
Patients with sepsis were sicker on admission and had a higher mortality.
CRP, PCT, IL-6 and LBP levels were significantly higher in patients with sepsis as compared to SIRS.
With PCT levels in the first 24 hours after ICU admission <2 ng/mL, ssepsis was virtually excluded (negative predictive value 97%).
With PCT >10 ng/mL, sepsis with bacterial infection was very likely (positive predictive value 88%).
PCT was best at discriminating between SIRS and sepsis with the highest area under the ROC curve (0.95, 95% CI 0.90–0.99).
Discussion.
This study showed that PCT is more useful than LBP, CRP and IL-6 in differentiating sepsis from SIRS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Meynaar, Iwan A.& Droog, Wouter& Batstra, Manou& Vreede, Rolf& Herbrink, Paul. 2011. In Critically Ill Patients, Serum Procalcitonin Is More Useful in Differentiating between Sepsis and SIRS than CRP, Il-6, or LBP. Critical Care Research and Practice،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-483640
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Meynaar, Iwan A.…[et al.]. In Critically Ill Patients, Serum Procalcitonin Is More Useful in Differentiating between Sepsis and SIRS than CRP, Il-6, or LBP. Critical Care Research and Practice No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-483640
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Meynaar, Iwan A.& Droog, Wouter& Batstra, Manou& Vreede, Rolf& Herbrink, Paul. In Critically Ill Patients, Serum Procalcitonin Is More Useful in Differentiating between Sepsis and SIRS than CRP, Il-6, or LBP. Critical Care Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-483640
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483640
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر