Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV : Past, Present, and Future
المؤلفون المشاركون
Harris, Marianne
Cohen, Calvin
Nosyk, Bohdan
Montaner, Julio S. G.
Harrigan, Richard
Lima, Viviane Dias
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-08
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
In the early years of the highly active antiretroviral therapy (HAART) era, HIV with resistance to two or more agents in different antiretroviral classes posed a significant clinical challenge.
Multidrug-resistant (MDR) HIV was an important cause of treatment failure, morbidity, and mortality.
Treatment options at the time were limited; multiple drug regimens with or without enfuvirtide were used with some success but proved to be difficult to sustain for reasons of tolerability, toxicity, and cost.
Starting in 2006, data began to emerge supporting the use of new drugs from the original antiretroviral classes (tipranavir, darunavir, and etravirine) and drugs from new classes (raltegravir and maraviroc) for the treatment of MDR HIV.
Their availability has enabled patients with MDR HIV to achieve full and durable viral suppression with more compact and cost-effective regimens including at least two and often three fully active agents.
The emergence of drug-resistant HIV is expected to continue to become less frequent in the future, driven by improvements in the convenience, tolerability, efficacy, and durability of first-line HAART regimens.
To continue this trend, the optimal rollout of HAART in both rich and resource-limited settings will require careful planning and strategic use of antiretroviral drugs and monitoring technologies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Harris, Marianne& Nosyk, Bohdan& Harrigan, Richard& Lima, Viviane Dias& Cohen, Calvin& Montaner, Julio S. G.. 2012. Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV : Past, Present, and Future. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-483737
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Harris, Marianne…[et al.]. Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV : Past, Present, and Future. AIDS Research and Treatment No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-483737
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Harris, Marianne& Nosyk, Bohdan& Harrigan, Richard& Lima, Viviane Dias& Cohen, Calvin& Montaner, Julio S. G.. Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV : Past, Present, and Future. AIDS Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-483737
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483737
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر