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High-Grade Prostate Cancer : Favorable Results in the Modern Era Regardless of Initial Treatment
المؤلفون المشاركون
Basler, Joseph W.
Swanson, Gregory P.
Ramahi, Emma H.
Jackson, Matthew W.
Du, Fei
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-01-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
We performed a retrospective study to determine the outcome of a modern cohort of patients with high-grade (Gleason score ≥ 8) prostate cancer treated with radical prostatectomy, radiation therapy, or hormone therapy.
Methods.
We identified 404 patients in the South Texas Veteran’s Healthcare System Tumor Registry diagnosed with high grade prostate cancer between 1998 and 2008.
Mean follow-up was 4.62 ± 2.61 years.
End points were biochemical failure-free survival, overall survival, metastasis-free survival, and cancer-specific survival.
Results.
5-year overall survival for patients undergoing radical prostatectomy, radiation therapy, and hormone therapy was 88.9%, 76.3%, and 58.9%, respectively.
5-year metastasis-free survival for patients undergoing radical prostatectomy, radiation therapy, and hormone therapy was 96.8%, 96.6%, and 88.4%, respectively, and 5-year cancer-specific survival was 97.2%, 100%, and 89.9%, respectively.
Patients with a Gleason score of 10 and pretreatment prostate-specific antigen > 20 ng/mL had decreased 5-year biochemical failure-free and cancer-specific survival.
Patients with a pretreatment prostate-specific antigen > 20 ng/mL had decreased 5-year overall survival.
Discussion.
Even for patients with high-grade disease, the outcome is not as dire in the modern era regardless of primary treatment modality chosen.
While there is room for improvement, we should not have a nihilistic impression of how these patients will respond to treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ramahi, Emma H.& Swanson, Gregory P.& Jackson, Matthew W.& Du, Fei& Basler, Joseph W.. 2012. High-Grade Prostate Cancer : Favorable Results in the Modern Era Regardless of Initial Treatment. ISRN Oncology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-483765
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ramahi, Emma H.…[et al.]. High-Grade Prostate Cancer : Favorable Results in the Modern Era Regardless of Initial Treatment. ISRN Oncology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-483765
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ramahi, Emma H.& Swanson, Gregory P.& Jackson, Matthew W.& Du, Fei& Basler, Joseph W.. High-Grade Prostate Cancer : Favorable Results in the Modern Era Regardless of Initial Treatment. ISRN Oncology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-483765
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483765
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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