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Rosmarinic Acid and Its Methyl Ester as Antimicrobial Components of the Hydromethanolic Extract of Hyptis atrorubens Poit. (Lamiaceae)
المؤلفون المشاركون
Biabiany, Murielle
Mahieux, Séverine
Sahpaz, Sevser
Roumy, Vincent
Standaert-Vitse, Annie
Rivière, Céline
Neut, Christel
Hennebelle, Thierry
Abedini, Amin
Bailleul, François
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-17
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Primary biological examination of four extracts of the leaves and stems of Hyptis atrorubens Poit.
(Lamiaceae), a plant species used as an antimicrobial agent in Guadeloupe, allowed us to select the hydromethanolic extract of the stems for further studies.
It was tested against 46 microorganisms in vitro.
It was active against 29 microorganisms.
The best antibacterial activity was found against bacteria, mostly Gram-positive ones.
Bioautography enabled the isolation and identification of four antibacterial compounds from this plant: rosmarinic acid, methyl rosmarinate, isoquercetin, and hyperoside.
The MIC and MBC values of these compounds and their combinations were determined against eight pathogenic bacteria.
The best inhibitory and bactericidal activity was found for methyl rosmarinate (0.3 mg/mL).
Nevertheless, the bactericidal power of rosmarinic acid was much faster in the time kill study.
Synergistic effects were found when combining the active compounds.
Finally, the inhibitory effects of the compounds were evaluated on the bacterial growth phases at two different temperatures.
Our study demonstrated for the first time antimicrobial activity of Hyptis atrorubens with identification of the active compounds.
It supports its traditional use in French West Indies.
Although its active compounds need to be further evaluated in vivo, this work emphasizes plants as potent sources of new antimicrobial agents when resistance to antibiotics increases dramatically.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abedini, Amin& Roumy, Vincent& Mahieux, Séverine& Biabiany, Murielle& Standaert-Vitse, Annie& Rivière, Céline…[et al.]. 2013. Rosmarinic Acid and Its Methyl Ester as Antimicrobial Components of the Hydromethanolic Extract of Hyptis atrorubens Poit. (Lamiaceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-484400
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abedini, Amin…[et al.]. Rosmarinic Acid and Its Methyl Ester as Antimicrobial Components of the Hydromethanolic Extract of Hyptis atrorubens Poit. (Lamiaceae). Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-484400
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abedini, Amin& Roumy, Vincent& Mahieux, Séverine& Biabiany, Murielle& Standaert-Vitse, Annie& Rivière, Céline…[et al.]. Rosmarinic Acid and Its Methyl Ester as Antimicrobial Components of the Hydromethanolic Extract of Hyptis atrorubens Poit. (Lamiaceae). Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-484400
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-484400
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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