Antithrombotic Medication for Cardioembolic Stroke Prevention
المؤلفون المشاركون
Arboix, Adrià
Krupinski, Jerzy
Font, M. Àngels
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-23، 23ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-22
دولة النشر
مصر
عدد الصفحات
23
التخصصات الرئيسية
الملخص EN
Embolism of cardiac origin accounts for about 20% of ischemic strokes.
Nonvalvular atrial fibrillation is the most frequent cause of cardioembolic stroke.
Approximately 1% of population is affected by atrial fibrillation, and its prevalence is growing with ageing in the modern world.
Strokes due to cardioembolism are in general severe and prone to early recurrence and have a higher long-term risk of recurrence and mortality.
Despite its enormous preventive potential, continuous oral anticoagulation is prescribed for less than half of patients with atrial fibrillation who have risk factors for cardioembolism and no contraindications for anticoagulation.
Available evidence does not support routine immediate anticoagulation of acute cardioembolic stroke.
Anticoagulation therapy's associated risk of hemorrhage and monitoring requirements have encouraged the investigation of alternative therapies for individuals with atrial fibrillation.
New anticoagulants being tested for prevention of stroke are low-molecular-weight heparins (LMWH), unfractionated heparin, factor Xa inhibitors, or direct thrombin inhibitors like dabigatran etexilate and rivaroxaban.
The later exhibit stable pharmacokinetics obviating the need for coagulation monitoring or dose titration, and they lack clinically significant food or drug interaction.
Moreover, they offer another potential that includes fixed dosing, oral administration, and rapid onset of action.
There are several concerns regarding potential harm, including an increased risk for hepatotoxicity, clinically significant bleeding, and acute coronary events.
Therefore, additional trials and postmarketing surveillance will be needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Font, M. Àngels& Krupinski, Jerzy& Arboix, Adrià. 2011. Antithrombotic Medication for Cardioembolic Stroke Prevention. Stroke Research and Treatment،Vol. 2011, no. 2011, pp.1-23.
https://search.emarefa.net/detail/BIM-484684
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Font, M. Àngels…[et al.]. Antithrombotic Medication for Cardioembolic Stroke Prevention. Stroke Research and Treatment No. 2011 (2011), pp.1-23.
https://search.emarefa.net/detail/BIM-484684
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Font, M. Àngels& Krupinski, Jerzy& Arboix, Adrià. Antithrombotic Medication for Cardioembolic Stroke Prevention. Stroke Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-23.
https://search.emarefa.net/detail/BIM-484684
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-484684
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر