Complete PSA Remission without Adjuvant Therapy after Secondary Lymph Node Surgery in Selected Patients with Biochemical Relapse after Radical Prostatectomy and Pelvic Lymph Node Dissection
المؤلفون المشاركون
Wawroschek, Friedhelm
Henke, Rolf-Peter
Winter, Alexander
Uphoff, Jens
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-26
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
To evaluate whether secondary resection of lymph node (LN) metastases (LNMs) can result in PSA remission, we analysed the PSA outcome after resection of LNM detected on PET/CT in patients with biochemical failure.
Materials and Methods.
11 patients with PSA relapse (mean 3.02 ng/mL, range 0.5–9.55 ng/mL) after radical prostatectomy without adjuvant therapy were included.
Suspicious LN (1–3) detected on choline PET/CT and nearby LN were openly dissected (09/04–02/11).
The PSA development was examined.
Histological and PET/CT findings were compared.
Results.
9 of 10 patients with histologically confirmed LNM showed a PSA response.
4 of 9 patients with single LNM had a complete permanent PSA remission (mean followup 31.8, range 1–48 months).
Of metastasis-suspicious LNs (14) 12 could be histologically confirmed.
The additionally removed 25 LNs were all correctly negative.
Conclusions.
The complete PSA remissions after secondary resection of single LNM argue for a feasible therapeutic benefit without adjuvant therapy.
For this purpose the choline PET/CT is in spite of its limitations currently the most reliable routinely available diagnostic tool.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Winter, Alexander& Uphoff, Jens& Henke, Rolf-Peter& Wawroschek, Friedhelm. 2011. Complete PSA Remission without Adjuvant Therapy after Secondary Lymph Node Surgery in Selected Patients with Biochemical Relapse after Radical Prostatectomy and Pelvic Lymph Node Dissection. Advances in Urology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-484867
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Winter, Alexander…[et al.]. Complete PSA Remission without Adjuvant Therapy after Secondary Lymph Node Surgery in Selected Patients with Biochemical Relapse after Radical Prostatectomy and Pelvic Lymph Node Dissection. Advances in Urology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-484867
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Winter, Alexander& Uphoff, Jens& Henke, Rolf-Peter& Wawroschek, Friedhelm. Complete PSA Remission without Adjuvant Therapy after Secondary Lymph Node Surgery in Selected Patients with Biochemical Relapse after Radical Prostatectomy and Pelvic Lymph Node Dissection. Advances in Urology. 2011. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-484867
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-484867
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر