Where Does Evidence from New Trials for Schizophrenia Fit with the Existing Evidence : A Case of the Emperor's New Clothes?
المؤلفون المشاركون
Rattehalli, Ranganath D.
Jayaram, Mahesh
Adams, Clive E.
المصدر
Schizophrenia Research and Treatment
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-04-08
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Advent of “atypical” antipsychotics has spawned new trials in the recent years and the number of such trial reports has been increasing exponentially.
As clinicians we have been led to believe that “atypicals” are better than “typicals” despite the odd dissenting voice in academic and clinical circles.
This has been largely ignored until the publication of two landmark, independent, pragmatic trials, Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) and Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS), which proved that thoughtfully chosen “typical” antipsychotics were as good as the newer “atypicals.” We pooled “leaving the study early data” from Cochrane Reviews that existed before CATIE and CUtLASS and added data from CATIE and CUtLASS to the pool for a “before and after” comparison.
Addition of CATIE and CUtLASS data only led to narrowing of the already existing confidence intervals, merely increasing precision, and decreasing the risk of Type II error.
Perhaps surprisingly, CATIE and CUtLASS when pooled with the already existing data showed us that we had chosen to turn a blind eye to findings that already existed.
This leads clinicians to question as to whether, in future, we need to feel less guilty about crying out early on that the emperor has no clothes on.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jayaram, Mahesh& Rattehalli, Ranganath D.& Adams, Clive E.. 2012. Where Does Evidence from New Trials for Schizophrenia Fit with the Existing Evidence : A Case of the Emperor's New Clothes?. Schizophrenia Research and Treatment،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-486155
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jayaram, Mahesh…[et al.]. Where Does Evidence from New Trials for Schizophrenia Fit with the Existing Evidence : A Case of the Emperor's New Clothes?. Schizophrenia Research and Treatment No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-486155
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jayaram, Mahesh& Rattehalli, Ranganath D.& Adams, Clive E.. Where Does Evidence from New Trials for Schizophrenia Fit with the Existing Evidence : A Case of the Emperor's New Clothes?. Schizophrenia Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-486155
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486155
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر