Response to Modified Antitubercular Drug Regime and Antiretroviral Therapy in a Case of HIV Infection with Disseminated Tuberculosis with Isoniazid Induced Toxic Epidermal Necrolysis
المؤلفون المشاركون
Gupta, Bhaskar
Bhattacharjee, Prithwiraj
Swami, Abhijit
المصدر
Case Reports in Infectious Diseases
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-05
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Toxic epidermal necrolysis (TEN) is a potentially life-threatening disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes.
Without proper management,TEN can cause sepsis leading to death of the patient.
Though TEN is commonly drug induced, Isoniazid (INH) has been uncommonly associated with TEN.
As INH is one of the first line drugs in treatment of tuberculosis, TEN induced INH needs modification of antitubercular therapy (ATT) with withdrawal of INH from the treatment regime along with other supportive treatments.
Patients with HIV infection and disseminated tuberculosis need to be urgently initiated on an effective ATT on diagnosis of tuberculosis.
However, if the patient develops potential life-threatening toxicity to first line antitubercular drugs like INH, an alternative effective ATT combination needs to be started as soon as the condition of the patient stabilizes as most of these patients present in advanced stage of HIV infection and this is to be followed by antiretroviral therapy (ART) as per guidelines.
The present case reports the effectiveness of an ATT regime comprising Rifampicin, Pyrazinamide, Ethambutol, and Levofloxacin along with ART in situations where INH cannot be given in disseminated tuberculosis in HIV patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Swami, Abhijit& Gupta, Bhaskar& Bhattacharjee, Prithwiraj. 2012. Response to Modified Antitubercular Drug Regime and Antiretroviral Therapy in a Case of HIV Infection with Disseminated Tuberculosis with Isoniazid Induced Toxic Epidermal Necrolysis. Case Reports in Infectious Diseases،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-486228
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Swami, Abhijit…[et al.]. Response to Modified Antitubercular Drug Regime and Antiretroviral Therapy in a Case of HIV Infection with Disseminated Tuberculosis with Isoniazid Induced Toxic Epidermal Necrolysis. Case Reports in Infectious Diseases No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-486228
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Swami, Abhijit& Gupta, Bhaskar& Bhattacharjee, Prithwiraj. Response to Modified Antitubercular Drug Regime and Antiretroviral Therapy in a Case of HIV Infection with Disseminated Tuberculosis with Isoniazid Induced Toxic Epidermal Necrolysis. Case Reports in Infectious Diseases. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-486228
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486228
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر