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Different Profile of Serum Leptin between Early Onset and Late Onset Preeclampsia
المؤلفون المشاركون
Naghavi, Anoosh
Salimi, Saeedeh
Farajian-Mashhadi, Farzaneh
Yaghmaei, Minoo
Shahrakipour, Mahnaz
Mokhtari, Mojgan
Saravani, Mohsen
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aim.
This study was designed to clarify the role of leptin and adiponectin in preeclampsia (PE) pathogenesis and different subtypes of preeclampsia.
Method.
This case control study was performed in 45 PE patients and 45 healthy controls matched for age, BMI, and ethnicity.
Serum leptin and adiponectin levels were determined by enzyme linked immunosorbent assay (ELISA).
Results.
Maternal serum leptin and adiponectin were significantly higher in PE women than controls.
Serum leptin was elevated in early onset preeclampsia (EOPE) and late onset preeclampsia (LOPE) compared to controls.
Among PE patients, serum leptin was higher in EOPE than LOPE women.
However, serum adiponectin was not different between EOPE and LOPE women.
The serum leptin was significantly higher in severe PE than mild PE.
The serum adiponectin was significantly elevated in severe PE compared to controls.
Significant positive correlation was observed between leptin and adiponectin and also between leptin and BMI in controls.
Moreover significant positive correlation was observed between adiponectin and BMI in PE patients and controls.
Conclusion.
The present study showed that serum leptin level may play a significant role as a biomarker to differentiate early and late onset PE and also its relation to BMI and severity of disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salimi, Saeedeh& Farajian-Mashhadi, Farzaneh& Naghavi, Anoosh& Mokhtari, Mojgan& Shahrakipour, Mahnaz& Saravani, Mohsen…[et al.]. 2014. Different Profile of Serum Leptin between Early Onset and Late Onset Preeclampsia. Disease Markers،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-486392
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salimi, Saeedeh…[et al.]. Different Profile of Serum Leptin between Early Onset and Late Onset Preeclampsia. Disease Markers No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-486392
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salimi, Saeedeh& Farajian-Mashhadi, Farzaneh& Naghavi, Anoosh& Mokhtari, Mojgan& Shahrakipour, Mahnaz& Saravani, Mohsen…[et al.]. Different Profile of Serum Leptin between Early Onset and Late Onset Preeclampsia. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-486392
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486392
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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