Natural Killer Cell Regulation by MicroRNAs in Health and Disease

المؤلفون المشاركون

Sullivan, Ryan P.
Leong, Jeffrey W.
Fehniger, Todd A.

المصدر

Journal of Biomedicine and Biotechnology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-11-19

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الطب البشري

الملخص EN

Natural killer (NK) cells are innate immune lymphocytes that are critical for normal host defense against infections and mediate antitumor immune responses.

MicroRNAs (miRNAs) are a family of small, noncoding RNAs that posttranscriptionally regulate the majority of cellular processes and pathways.

Our understanding of how miRNAs regulate NK cells biology is limited, but recent studies have provided novel insight into their expression by NK cells, and how they contribute to the regulation of NK cell development, maturation, survival, and effector function.

Here, we review the expression of miRNAs by NK cells, their contribution to cell intrinsic and extrinsic control of NK cell development and effector response, and their dysregulation in NK cell malignancies.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Leong, Jeffrey W.& Sullivan, Ryan P.& Fehniger, Todd A.. 2012. Natural Killer Cell Regulation by MicroRNAs in Health and Disease. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-486734

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Leong, Jeffrey W.…[et al.]. Natural Killer Cell Regulation by MicroRNAs in Health and Disease. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-486734

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Leong, Jeffrey W.& Sullivan, Ryan P.& Fehniger, Todd A.. Natural Killer Cell Regulation by MicroRNAs in Health and Disease. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-486734

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-486734